Evidence map›Paper›PMID 42832093›Full record

SynthesisNeurosurgical review2026

Morphometric findings of the subaxial cervical spine among different geographic regions and the implications for cervical pedicle screw placement: a systematic review and meta-analysis.

Raphael Bastianon Santiago, Esteban Quiceno, Mohamed A R Soliman, Jacob D Greisman, Isabelle G Stockman, Hannon W Levy, Rehman Ali Baig, Asham Khan, Alexander G Fritz, John Pollina and 1 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Raphael Bastianon Santiago *Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Esteban Quiceno *Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.ORCID http://orcid.org/0000-0001-8967-1545
Mohamed A R SolimanDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.ORCID http://orcid.org/0000-0003-1855-2551
Jacob D GreismanDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Isabelle G StockmanJacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Hannon W LevyThe George Washington University School of Medicine and Health Sciences, Washington, DC, USA.ORCID http://orcid.org/0000-0003-2855-6628
Rehman Ali BaigDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Asham KhanDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.ORCID http://orcid.org/0000-0003-2593-8831
Alexander G FritzDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
John PollinaDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.ORCID http://orcid.org/0000-0002-6234-4517
Jeffrey P MullinDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA. jmullin@ubns.com.ORCID http://orcid.org/0000-0003-0640-2329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlthough cervical pedicle screws (CPS) improve outcomes in trauma and deformity surgery, existing morphometric studies have not been systematically consolidated. This systematic review aims to pool available data to characterize subaxial cervical pedicle dimensions and insertion angles across geographically diverse populations and evaluate population-level anatomical variation relevant to cervical pedicle screw planning.

methodsPubMed, Embase, and Google Scholar were searched to identify anatomical studies published between database inception and August 1, 2024 that reported computed tomography (CT) measurements obtained from at least 10 patients who underwent CPS placement or from at least 10 cadaveric specimens. Five measurements in these studies were analyzed: pedicle width (PW), pedicle height, mean screw length, pedicle transverse angle (PTA), and the difference between the widest and narrowest PTA along the subaxial cervical spine. Pooled means were analyzed for all subaxial vertebrae from patients in the different geographic regions identified during our literature search.

resultsForty-eight articles comprising 4014 patients from 18 countries in East Asia, Southern Asia, Southeast Asia, the Middle East, the USA, Europe, and East Africa were included. Statistically significant differences in PW were observed across geographic groups at the C3, C5, C6, and C7 vertebral levels, with the largest mean pedicle dimensions found in East Asian populations and the smallest in South Asian populations. Additionally, PW was consistently greater in men than women at all levels. PTA was significantly different between subgroups at C7, where the sharpest PTA was recorded in the East Asia subgroup (p < 0.05).

conclusionThis study identified population-level differences in cervical pedicle morphology across geographic regions that may inform individualized preoperative planning. Future studies correlating morphometric variation with surgical outcomes are needed.

Indexed as

Cervical VertebraePedicle ScrewsSpinal FusionFemaleHumansCervical spineComputed tomographyMorphologyMorphometryPedicle screwSubaxial cervical spine

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.