ArticleAbdominal radiology (New York)2026
Preoperative FDG PET/CT topographic patterns and clinical parameters are associated with incomplete cytoreduction in peritoneal carcinomatosis: proposal of the Resectability Score.
Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo explore associations between preoperative FDG PET/CT-derived topographic patterns, clinical variables, and unfavorable surgical outcome (incomplete cytoreduction or intraoperative unresectability) in peritoneal carcinomatosis (PC), and to propose a simple, transparent, preoperatively applicable Resectability Score (RS) as a hypothesis-generating tool for future prospective validation.
methodsIn this single-center retrospective cohort study (May 2018-April 2026), 39 patients with histopathologically confirmed PC who underwent surgical exploration were included. Univariable associations between PET/CT variables (PET-estimated Peritoneal Cancer Index [PCI] category, mesenteric root uptake, retroperitoneal uptake) and clinical factors and the composite endpoint were assessed. Given the limited number of outcome events, no multivariable model was fitted. The RS was proposed conceptually, with weights reflecting the strength of the observed associations, and its performance was deliberately not assessed in this dataset.
resultsEighteen of 39 patients (46.2%) had an unfavorable outcome (CC-2/3, n = 12; intraoperative unresectability, n = 6). PET-estimated PCI > 20 (OR 9.4, 95% CI 2.0-44.3; p = 0.003), mesenteric root FDG uptake (0/21 vs. 6/18; p = 0.006), and retroperitoneal FDG uptake (0/21 vs. 6/18; p = 0.006) were significantly associated with unfavorable outcome; gastric primary tumor showed a non-significant trend (OR 4.8, 95% CI 1.0-22.3; p = 0.07). Among 33 patients who underwent CRS + HIPEC, complete cytoreduction rates by PET-estimated PCI category were 85.7% (PCI ≤ 10), 63.6% (PCI 11-20), and 25.0% (PCI > 20) (p = 0.017). All six unresectable patients had shown mesenteric root or retroperitoneal FDG uptake preoperatively.
conclusionPreoperative FDG PET/CT topographic patterns in particular high disease burden and mesenteric root or retroperitoneal uptake are associated with unfavorable surgical outcomes in PC. The proposed RS is a hypothesis-generating tool only; formal derivation, internal validation, and external validation are required before any clinical application.
Indexed as
Identifiers
42832036What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.