Evidence map›Paper›PMID 42831962›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

MASCC oncodermatology clinical practice statement: prevention of acute radiation dermatitis using barrier-forming topical agents.

Shirley S W Tse, Shely Kagan, Britney Zhang, Christina Yang, Shivani Verma, Henry C Y Wong, Shing Fung Lee, Julie Ryan Wolf, Corina van den Hurk, Raymond J Chan and 7 more

Abstract readConsensus StatementReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shirley S W TseDepartment of Oncology, United Christian Hospital, Kowloon East Cluster, Hospital Authority, Hong Kong, China. shirley.sw.tse@gmail.com.
Shely KaganDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.
Britney ZhangDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.
Christina YangDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.
Shivani VermaDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.
Henry C Y WongDepartment of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Shing Fung LeeDepartment of Radiation Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.
Julie Ryan WolfDepartment of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.
Corina van den HurkUtrecht and Catharina Hospital, Eindhoven, The Netherlands.
Raymond J ChanCaring Futures Institute, College of Health and Enablement, Flinders University, Adelaide, South, Australia.
Patries M HerstDepartment of Radiation Therapy, University of Otago, Wellington, New Zealand.
Tarek HijalDepartment of Oncology, Division of Radiation Oncology, McGill University, Montreal, Canada.
Carmen Helena Avella BolivarDepartment of Oncology, Division of Radiation Oncology, McGill University, Montreal, Canada.
Edward ChowDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.
Pierluigi BonomoRadiation Oncology, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.
Gustavo Nader MartaDepartment of Radiation Oncology, Hospital Sírio-Libanês, São Paulo, Brazil.
Multinational Association of Supportive Care in Cancer (MASCC) Oncodermatology Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMASCC Clinical Practice Statements (CPS) are practice-oriented resources designed to support clinicians by addressing areas of clinical need where high-quality evidence is limited. They reflect expert consensus on current practices, treatment approaches, and modalities commonly used in oncology care. This CPS aims to provide practical guidance for the prevention of acute radiation dermatitis (ARD) using barrier-forming topical agents.

methodsThis CPS was developed based on a comprehensive review of the literature identified through MEDLINE, EMBASE, and Cochrane CENTRAL conducted up to April 23, 2026, followed by structured discussions among experts from the MASCC Oncodermatology Study Group. The findings were synthesized into bullet points to provide a practical guide to optimal standard-of-care practices.

resultsRecommendations were developed to guide patient selection, skin preparation, product choice, application schedule and technique, as well as monitoring when initiating, using, and ceasing when using barrier-forming topical agents for the prevention of ARD, with the best available evidence.

conclusionsBarrier-forming topical agents are recommended for patients undergoing radiotherapy who are at considerable risk of developing high‑grade ARD, particularly in treatment sites with irregular anatomical contours, such as head and neck cancers. Extension to other anatomical subsites may be considered; however, more robust data are required to support their routine use in these settings. Among these agents, StrataXRT currently has the most robust supporting evidence.

Indexed as

Dermatologic AgentsNeoplasmsRadiodermatitisAcute DiseaseAdministration, TopicalHumansPatient SelectionDermatologic AgentsAcute radiation dermatitisBarrier-forming topical agentsClinical practice statement

Identifiers

PMID42831962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.