Evidence map›Paper›PMID 42831953›Full record

ArticleArchives of osteoporosis2026

Anti-osteoporosis medications in persons with and without Parkinson disease in Finland.

Miriam T Y Leung, Marja-Leena Lamidi, Miia Tiihonen, Sirpa Hartikainen, J Simon Bell, Justin P Turner, Anna-Maija Tolppanen

Abstract read
In one paragraph

Article in Archives of osteoporosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Miriam T Y LeungCentre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, Australia. miriam.leung77@monash.edu.
Marja-Leena LamidiSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Miia TiihonenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Sirpa HartikainenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
J Simon BellCentre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, Australia.
Justin P TurnerCentre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, Australia.
Anna-Maija TolppanenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.

Funding

Australian Government Australian Government Research Training Scholarship
6 · The paper itself

Abstract

Contrary to reports on under-treatment in persons with Parkinson's disease, our study found similar anti-osteoporosis medication usage before and after their hip fractures among Finns with and without Parkinson's disease. Additional preventive measures may be needed to mitigate the high risk of hip fractures among persons with Parkinson's disease. PURPOSE: Parkinson's disease (PD) is associated with a doubled risk of hip fracture. However, previous reports suggest under-recognition of osteoporosis among persons with PD. Our study aimed to assess the annual prevalence of anti-osteoporosis medications among persons with and without PD in relation to diagnosis of PD and hip fractures.

methodsOur nationwide matched cohort design included 33,153 persons diagnosed with incident PD between 2000 and 2009 in Finland and 1:2 matched comparison cohort. Persons with previous hip fractures were excluded. Annual prevalences of anti-osteoporosis medications were calculated for each year between 5 years before and 10 years after diagnosis of PD, and between 5 years before and 5 years after the incident hip fractures.

resultsPrevalence of anti-osteoporosis medications was higher in persons with PD (3.62%, 95% confidence interval [CI] 3.28-3.98%) than those without PD (2.91%, 95% CI 2.70-3.14%), starting from 3 years before the diagnosis. Among individuals with incident hip fractures (1475 [13%] persons with PD and 1371 [6%] persons without PD), the annual prevalence were similar among persons with PD and without PD, peaking within 1 year after hip fractures (with PD: 20.3%, 95% CI 18.0-22.8%; without PD: 21.0%, 95% CI 18.5-23.6%).

conclusionContrary to reports on under-treatment in persons with PD, our study found similar anti-osteoporosis medication usage before and after their hip fractures among Finns with and without PD. Additional preventive measures, such as regular review of fall risk, is needed to mitigate the doubled risk of hip fracture in PD.

Indexed as

Bone Density Conservation AgentsHip FracturesOsteoporosisParkinson DiseaseAgedAged, 80 and overCohort StudiesFemaleFinlandHumansMaleMiddle AgedPrevalenceBone Density Conservation AgentsAntiresorptive medicationHip fractureOsteoporosisParkinson’s disease

Identifiers

PMID42831953
PMCPMC13638689

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.