Evidence map›Paper›PMID 42831670›Full record

ArticleEuropean stroke journal2026

Early change and new onset of vascular pathology in cervical artery dissection: implications for surveillance.

Robin Seihu, Tobias Hofmann, Frank Dömges, Hakan Cangür, Martin Döltz, Jens Neumann, Steffen Eue, Alexander Knörnschild, Daniel Behme, Stefanie Schreiber and 2 more

Abstract read
In one paragraph

Article in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Robin SeihuDepartment of Neurology, Magdeburg University Hospital, Magdeburg, Germany.ORCID 0009-0000-7730-4430
Tobias HofmannCentral Emergency Department, Magdeburg University Hospital, Magdeburg, Germany.
Frank DömgesDepartment of Neurology, Harzklinikum Wernigerode, Wernigerode, Germany.
Hakan CangürDepartment of Neurology, Klinikum Wolfsburg, Wolfsburg, Germany.
Martin DöltzDepartment of Neurology, Ameos-Klinikum Haldensleben, Haldensleben, Germany.
Jens NeumannDepartment of Neurology, Magdeburg University Hospital, Magdeburg, Germany.ORCID 0009-0002-6211-1227
Steffen EueDepartment of Neurology, Ameos-Klinikum Bernburg, Bernburg, Germany.
Alexander KnörnschildDepartment of Neurology, Ameos-Klinikum Bernburg, Bernburg, Germany.
Daniel BehmeDepartment of Neuroradiology, Magdeburg University Hospital, Magdeburg, Germany.ORCID 0000-0002-5353-9515
Stefanie SchreiberDepartment of Neurology, Magdeburg University Hospital, Magdeburg, Germany.ORCID 0000-0003-4439-4374
Michael GörtlerDepartment of Neurology, Magdeburg University Hospital, Magdeburg, Germany.
For The Tasc-San Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntithrombotic therapy is central to stroke prevention after spontaneous cervical artery dissection (sCAD), but its efficacy may depend on the underlying vascular morphology. We examined the temporal course of vascular changes after sCAD. PATIENTS AND

methodsConsecutive patients with first-time sCAD underwent prospective serial duplex sonography for up to 10 years. In this retrospective cohort analysis, pathology change was defined as recanalisation of an occluded artery or progression from stenosis to occlusion. New pathology resulting from dissection recurrence was considered if an occlusion occurred in the presence of pre-existing stenosis or vice versa.

resultsIn total, 159 patients (83 men; mean age 44.8 years) with first-time sCAD were followed-up starting 1.3 days (median) after symptom onset. Bilateral dissections occurred in 6 patients and recurrent dissections in 26 arteries, resulting in follow-up of 191 arteries (108 internal carotid, 83 vertebral). Recanalisation occurred in 40/80 occluded arteries (cumulative rate 70.4%), whereas progression to occlusion occurred in 9/109 stenosed arteries (10.0%). All changes except one (recanalisation) occurred within 4 months. Recurrent dissection occurred within 6 weeks in 20 patients (14.7%) and between 2 and 7 years in 7 patients (13.7%). Overall, 62 vascular changes or new pathologies were observed in 50 patients (31.4%), with 42 occurring within the first 6 weeks.

conclusionsUnder intensive surveillance, vessel morphology after sCAD is highly dynamic during the early phase, with frequent recanalisation and recurrent dissection. Structured early vascular follow-up may be important if evolving vessel morphology is to guide future individualised antithrombotic treatment strategies.

Indexed as

Carotid Artery, Internal, DissectionVertebral Artery DissectionAdultAgedDisease ProgressionDissection, Blood VesselFemaleFollow-Up StudiesHumansMaleMiddle AgedRecurrenceRetrospective Studiesanticoagulantsantiplatelet agentscervical artery dissectiondissection recurrencerecanalisation

Identifiers

PMID42831670
PMCPMC13636090

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