Evidence map›Paper›PMID 42831637›Full record

ArticleAntimicrobial agents and chemotherapy2026

Screening of a chemogenetic library unveils dual-stage antiplasmodials with low cytotoxicity.

Laura Torres, Matthew E Fishbaugher, Melanie Lam, Alexander T Chao, Calla Martyn, Luying Pei, Debapriya Sengupta, Maxime Dauphinais, Jonathan E Gable, Srinivasa P S Rao and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Laura TorresOpen Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Matthew E FishbaugherGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Melanie LamOpen Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Alexander T ChaoGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Calla MartynDiscovery Sciences, Biomedical Research, Novartis, Emeryville, California, USA.
Luying PeiGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Debapriya SenguptaGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Maxime DauphinaisGlobal Discovery Chemistry, Biomedical Research, Novartis, Emeryville, California, USA.
Jonathan E GableGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Srinivasa P S RaoGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.ORCID 0000-0002-7156-5725
Steffen RennerDiscovery Sciences, Biomedical Research, Novartis, Basel, Switzerland.
W Armand GuiguemdeGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Sebastian A MikolajczakGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.
Anke HarupaGlobal Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.ORCID 0009-0009-5062-849X
Gabriel MitchellOpen Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, California, USA.ORCID 0000-0001-7977-5316

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global effort to eradicate malaria requires the development of drugs with novel mechanisms of action and differentiated pharmacological profiles. Both liver and blood phases of

Indexed as

AntimalarialsPlasmodium bergheiPlasmodium falciparumSmall Molecule LibrariesAnimalsCell SurvivalChemogeneticsHumansLiverMalariaMiceAntimalarialsSmall Molecule Librariesblooddrug discoveryglobal healthlivermalariaPlasmodium

Identifiers

PMID42831637
PMCPMC13731184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.