ArticleArthroplasty today2026
Efficacy of Noninvasive Interventions for Reducing Postoperative Kinesiophobia in Patients Undergoing Primary Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Article in Arthroplasty today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Excessive fear of movement (kinesiophobia) hinders functional recovery after total knee arthroplasty. We evaluated the efficacy of noninvasive interventions in reducing postoperative kinesiophobia. Methods: We systematically searched PubMed, Embase, Scopus, and Web of Science for randomized controlled trials comparing noninvasive strategies with usual care, from inception to December 10, 2025. Risk of bias was evaluated using the Cochrane Risk of Bias 2 (RoB 2) tool. We pooled data using a random-effects meta-analysis to calculate mean differences (MD). The primary outcome was the Tampa Scale of Kinesiophobia (TSK). The certainty of evidence was appraised via the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Results: Sixteen randomized controlled trials (n = 1373) were included. Interventions were categorized into rehabilitation, cognitive-behavioral therapy (CBT), patient education, and adjunctive modalities. Meta-analysis indicated that rehabilitation and exercise programs significantly reduced TSK scores (MD = -7.95; 95% confidence interval: -13.15 to -2.74; Conclusions: Structured rehabilitation and exercise programs and CBT-based interventions were associated with significant reductions in kinesiophobia after total knee arthroplasty, although the certainty of evidence was moderate for rehabilitation and exercise and low for psychotherapy and CBT. Emerging modalities also showed favorable results, but the available evidence remains limited. Level of Evidence: I.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.