ArticleCureus2026
Isolated Aphasia as an Epileptic Manifestation of Neurosarcoidosis: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute aphasia requires urgent evaluation for stroke, but recurrent and stereotyped language disturbances may also reflect focal seizures. We report the case of a 23-year-old man brought to the emergency department (ED) with aphasia that had been present for approximately six hours. Over the preceding week, he had experienced several similar but briefer episodes that had resolved spontaneously. He was concurrently undergoing investigation at another institution for persistent hiccups and near-daily vomiting of more than one month's duration. Chest computed tomography (CT) and positron emission tomography (PET)-computed tomography had already shown mediastinal and mesenteric lymphadenopathy suggestive of sarcoidosis, although other etiologies, including malignancy, could not be excluded. Neurological examination was limited by the language disturbance but showed no obvious motor deficit. Brain computed tomography revealed obstructive hydrocephalus with transependymal cerebrospinal fluid flow and multiple enhancing nodular lesions, predominantly in and around the ventricular system. Electroencephalography demonstrated epileptiform activity, and the aphasia resolved after treatment with levetiracetam and clobazam. Further cerebrospinal fluid analysis, magnetic resonance imaging (MRI), and pathological investigations supported a diagnosis of probable neurosarcoidosis presenting with lymphocytic meningoencephalitis and obstructive hydrocephalus. This case illustrates an unusual pathophysiological sequence, isolated aphasia as a focal epileptic manifestation of neurosarcoidosis, and is a reminder that unexplained focal neurological symptoms, particularly when fluctuating or recurrent, warrant the consideration of seizures and early electroencephalography.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.