Evidence map›Paper›PMID 42831022›Full record

ArticleCureus2026

Mimicking Polycystic Liver Disease: A Case Report of Innumerable Cystic Hepatic Metastases From a Pancreatic Neuroendocrine Tumour and Diagnostic Role of Endoscopic Ultrasound.

Qais Payab, Rida Abbasi, Mohammed Korani, Ajith Siriwardena, Venkata Pk Lekharaju, Daniyal Baig, Javaid Iqbal, Sajjad Mahmood

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qais PayabGastroenterology and Hepatology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Rida AbbasiGastroenterology and Hepatology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Mohammed KoraniGastroenterology and Hepatology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Ajith SiriwardenaHepato-Pancreato-Biliary Surgery, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, GBR.
Venkata Pk LekharajuGastroenterology and Hepatology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Daniyal BaigGastroenterology and Hepatology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Javaid IqbalGastroenterology and Hepatology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Sajjad MahmoodGastroenterology and Hepatology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine tumours (PNETs) are malignant processes and are identified as being the rarest of all pancreatic cancers. Here we present the case of a 62-year-old male with a background of chronic lymphocytic leukaemia (CLL) who was investigated over 18 months for progressive hepatic cystic lesions with no known aetiology. Imaging revealed main pancreatic duct dilatation without an identifiable intrinsic or extrinsic cause, coupled with enlarged mesenteric lymph nodes. Endoscopic ultrasound identified multiple cystic liver lesions of different sizes, some reflecting the presence of septations. The calibre of the main pancreatic duct was noted to be dilated in the absence of calculi, raising suspicion for a focal inflammatory process or chronic pancreatitis. Fine needle aspiration was performed from the pancreas, liver and lymph nodes; samples were sent for cytological analysis. This revealed the presence of a well-differentiated neuroendocrine tumour, WHO grade 2, across all three sites. The neuroendocrine multidisciplinary team (MDT) classified the tumor as stage T1N1M1a and recommended treatment with somatostatin analogue with palliative intent. This case reflects the diagnostic challenges of atypical PNET presentations and emphasises the crucial role of endoscopic ultrasound with tissue sampling in establishing a definitive diagnosis.

Indexed as

chronic lymphoid leukemiaendoscopic ultrasound (eus)fine needle aspiration (fna)hepatic metastasesliver cystsmain pancreatic duct dilatationnonfunctional pancreatic neuroendocrine tumorpancreatic neuroendocrine tumorswell-differentiated neuroendocrine tumor (wdnet)who grade 2

Identifiers

PMID42831022
PMCPMC13634188

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.