ArticleOpen respiratory archives
Prevalence and Maintenance of Clinical Remission in Patients with Severe Uncontrolled Asthma Undergoing Biologic Therapies.
Article in Open respiratory archives. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Clinical remission is an emerging treatment goal in severe asthma, although real-world data on its long-term maintenance remain limited. We retrospectively evaluated 50 patients who initiated first-line biologic therapy with omalizumab, mepolizumab, or reslizumab between 2015 and 2019. Clinical remission at 12 months was defined as no moderate or severe exacerbations, an asthma control test (ACT) score of ≥20, post-bronchodilator forced expiratory volume in 1 second of ≥80% predicted, and no use of maintenance oral corticosteroid. Of these patients, 13 (26.0%) met the criteria for remission. They had significantly higher unadjusted baseline forced vital capacities (FVC; 103.6% vs. 85.7%,
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