Evidence map›Paper›PMID 42830855›Full record

ArticleJournal of surgical case reports2026

Anterior rib giant cell tumor of bone mimicking a malignant chest-wall tumor: a case report.

Mami Yamamoto, Masanori Ishida, Yuichi Ichikawa, Maki Tanigawa, Ai Enomoto, Akitoshi Kanagawa, Jun Nishida, Toshitaka Nagao, Kazuhiro Saito

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mami YamamotoDepartment of Radiology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Masanori IshidaDepartment of Radiology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.ORCID https://orcid.org/0000-0001-6804-4761
Yuichi IchikawaDepartment of Orthopedic Surgery, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Maki TanigawaDepartment of Anatomic Pathology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Ai EnomotoDepartment of Anatomic Pathology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Akitoshi KanagawaDepartment of Radiology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Jun NishidaDepartment of Orthopedic Surgery, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Toshitaka NagaoDepartment of Anatomic Pathology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Kazuhiro SaitoDepartment of Radiology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell tumor of bone (GCTB) rarely arises in the rib, and anterior rib involvement may mimic malignant chest-wall tumors. A 44-year-old woman presented with a palpable mass in the left anterior chest wall. Computed tomography (CT) revealed an osteolytic mass arising from the anterior left third rib, enlarging from 31 to 55 mm over ~2 months. Magnetic resonance imaging showed diffusion restriction, and fluorodeoxyglucose positron emission tomography/CT demonstrated intense uptake with a maximum standardized uptake value of 15.7, raising suspicion for malignancy. Needle biopsy suggested GCTB, but malignancy could not be excluded. Wide resection of the left second to fourth ribs was performed. Histology showed no sarcomatous transformation, and nuclear histone H3.3 with a glycine-to-tryptophan substitution at amino acid position 34 positivity in mononuclear tumor cells supported the diagnosis of GCTB. The patient remained recurrence-free for ~2 years. Anterior rib GCTB can mimic malignancy, requiring integrated radiological and pathological evaluation.

Indexed as

chest wall tumorFDG-PET/CTGiant cell tumor of boneH3.3 G34Wrib tumor

Identifiers

PMID42830855
PMCPMC13633881

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