ArticleArthroplasty today2026
Arthroplasty in Individuals With Skeletal Dysplasias: Updated Surgical Outcomes and Complications Following Multidisciplinary Preoperative Screening.
Article in Arthroplasty today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: Skeletal dysplasias are a heterogeneous group of genetic disorders characterized by atypical cartilage and bone development. Affected individuals often experience joint pain and asymmetric alignment, leading to early-onset degenerative joint disease requiring early surgical intervention. This study provides an updated analysis of patients with skeletal dysplasias undergoing arthroplasty at a single institution following implementation of a multidisciplinary preoperative screening protocol, including implant survival and complications by type of procedure. Methods: This institutional review board-approved, retrospective study included 55 skeletal dysplasia patients who underwent total hip and/or knee arthroplasty at Hospital for Special Surgery in New York, NY, between April 1985 and June 2024. Chart review included demographics, history, imaging studies, surgical indications, and complications. Results: Fifty-five individuals had 103 arthroplasties, including 75 hips and 28 knees. Almost half of hips (49%) and knees (54%) required custom components. Fifteen of 75 hip surgeries and 6/28 knee surgeries were revisions. Five-year implant survival was 86.6% for hips and 88.7% for knees. Implant survival at 10 years was 86.6% for hips and 59.1% for knees; hip survival at 20 years was 57.7%. Postoperative complications occurred in 29/75 hip arthroplasties (38.7%) and 15/28 knee arthroplasties (53.6%), although orthopaedic/surgical complications were less frequent, affecting 8/75 hip arthroplasties (10.7%) and 3/28 knee arthroplasties (10.7%). Conclusions: Presurgical advance planning remains essential in this patient population, including custom component design. Surgeries performed after 2018, when preoperative consultation with a dedicated multidisciplinary skeletal dysplasia team was initiated, showed a reduction in complication severity, highlighting improvements in care associated with specialized perioperative management.
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