Evidence map›Paper›PMID 42830770›Full record

ArticleJournal of Taibah University Medical Sciences2026

Metabolic effects of periodontal pathogens

Divya Gopinath, Balachandar Selvakumar, Priyadharshini Sekar, Marwan M Mohammed, Zhengrui Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Taibah University Medical Sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Divya GopinathBasic Medical and Dental Sciences Department, College of Dentistry, Ajman University, United Arab Emirates.
Balachandar SelvakumarMicrobiota Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Priyadharshini SekarMicrobiota Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Marwan M MohammedMicrobiota Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Zhengrui LiDepartment of Oral and Maxillofacial-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontal pathogens are increasingly recognized as key regulators of cancer biology. However, their roles in modulating metabolism-related gene expression in colorectal cancer remain poorly understood. Methods: Human colorectal cancer (HCT)116 cells were exposed to Results: Conclusion: The distinct impacts of the two bacterial species demonstrated the complexity of colorectal cancer host-microbiome interactions. These findings suggest that microbial species may influence tumor biology through different metabolic processes, leading to diverse rather than uniform metabolic changes in colorectal cancer cells.

Indexed as

CancerFusobacterium nucleatumOral bacteriaPathogenPorphyromonas gingivalis

Identifiers

PMID42830770
PMCPMC13634108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.