Evidence map›Paper›PMID 42830743›Full record

ArticleCureus2026

Epstein-Barr Virus-Positive Nonkeratinizing Squamous Cell Carcinoma (Lymphoepithelioma-Like Carcinoma) of the Medial Periorbital Area: A Case Report.

Stella Hayrapetyan, Isabel Randolph, Nithin Thummala, Fulvio Lonardo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stella HayrapetyanPathology, Detroit Medical Center, Detroit, USA.
Isabel RandolphOtolaryngology, Detroit Medical Center, Detroit, USA.
Nithin ThummalaRadiology, The Barbara Ann Karmanos Cancer Institute, Detroit, USA.
Fulvio LonardoPathology, The Barbara Ann Karmanos Cancer Institute, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV)-positive nonkeratinizing squamous cell carcinoma (NKSCC), formerly referred to as lymphoepithelioma or lymphoepithelioma-like carcinoma, most commonly arises in the nasopharynx. However, it has been reported in multiple extra-nasopharyngeal sites. Orbital involvement is exceedingly rare, with most reported cases occurring in the ocular adnexa. We present the case of a 67-year-old Asian male with EBV-positive NKSCC of the medial periorbital area who developed right-sided diplopia and periocular edema. Recognition of this rare entity and its diagnostic features is essential for accurate diagnosis and appropriate management.

Indexed as

eberebvhead and neck malignancieslymphoepithelioma-like carcinomamedial canthus massnonkeratinizing carcinomaorbital ct imagingorbital exenterationperiorbital tumorsquamous cell carcinoma

Identifiers

PMID42830743
PMCPMC13633858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.