Evidence map›Paper›PMID 42830602›Full record

ReviewNucleus (Austin, Tex.)2026

Redundant mispair excision mechanisms in eukaryotic DNA mismatch repair.

Christopher D Putnam, Richard D Kolodner

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nucleus (Austin, Tex.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher D PutnamDepartment of Pediatrics, University of California School of Medicine, San Diego, La Jolla, CA, USA.ORCID 0000-0002-6145-1265
Richard D KolodnerMoores-UCSD Cancer Center, University of California School of Medicine, San Diego, La Jolla, CA, USA.ORCID 0000-0002-4806-8384

Funding

ENZYMOLOGY OF MISMATCH REPAIR IN YEASTR01GM050006 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard D Kolodner · 1994 to 2026
$10.5M
NIGMS NIH HHS R01 GM050006
6 · The paper itself

Abstract

DNA mismatch repair (MMR) corrects DNA replication errors, some forms of chemical damage to DNA bases, and acts in processes such as heteroduplex rejection, triplet repeat expansion, antibody maturation and cytotoxicity of alkylating agents. During MMR, the newly synthesized DNA strand containing the error must be removed and resynthesized to prevent mutations. In bacteria, this strand is displaced by the UvrD DNA helicase. In eukaryotes, this strand is excised by redundant pathways. In the first excision pathway identified,

Indexed as

DNA Mismatch RepairAnimalsExcision RepairExodeoxyribonucleasesHumansSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteinsexodeoxyribonuclease IExodeoxyribonucleasesSaccharomyces cerevisiae ProteinsDNA mismatch repairexonuclease 1 (Exo1)flap endonuclease 1mispair excisionMlh1-Pms1 endonuclease

Identifiers

PMID42830602
PMCPMC13644597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.