Evidence map›Paper›PMID 42830468›Full record

ArticleNMR in biomedicine2026

Validation of a Novel, Low-Cost, Portable MRI-Compatible Exercise Device in Healthy Volunteers and Patients With Pulmonary Hypertension.

Ruta Virsinskaite, James T Brown, Tushar Kotecha, Darren Bower, Jennifer A Steeden, Javier Montalt-Tordera, Olivier Jaubert, Marianna Fontana, J Gerry Coghlan, Daniel S Knight and 1 more

Abstract readValidation Study
In one paragraph

Article in NMR in biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruta VirsinskaiteNational Pulmonary Hypertension Service, Royal Free London NHS Foundation Trust, London, UK.ORCID https://orcid.org/0009-0009-3988-9066
James T BrownNational Pulmonary Hypertension Service, Royal Free London NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0003-1541-4081
Tushar KotechaNational Pulmonary Hypertension Service, Royal Free London NHS Foundation Trust, London, UK.
Darren BowerEngineering Department, Royal Free London NHS Foundation Trust, London, UK.
Jennifer A SteedenInstitute of Cardiovascular Science, University College London, London, UK.ORCID https://orcid.org/0000-0002-9792-2022
Javier Montalt-TorderaInstitute of Cardiovascular Science, University College London, London, UK.
Olivier JaubertInstitute of Cardiovascular Science, University College London, London, UK.ORCID https://orcid.org/0000-0002-7854-4150
Marianna FontanaDepartment of Cardiac MRI, Royal Free London NHS Foundation Trust, London, UK.
J Gerry CoghlanNational Pulmonary Hypertension Service, Royal Free London NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-3424-5888
Daniel S KnightNational Pulmonary Hypertension Service, Royal Free London NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-0512-3961
Vivek MuthuranguInstitute of Cardiovascular Science, University College London, London, UK.ORCID https://orcid.org/0000-0002-4292-6456

Funding

BHF Intermediate Fellowship FS/18/21/33447British Heart Foundation (BHF) Clinical Research Leave Fellowship FS/CRLF/20/23004National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC)
6 · The paper itself

Abstract

The value of exercise cardiovascular magnetic resonance (CMR) has been shown in many clinical scenarios. We have developed a novel MR-compatible exercise device and aim to validate it against the reference standard MR-conventional ergometer. The novel device consisted of two half-pipes fixed to a wooden base, with participants wearing knee-length socks with a 0.5 kg weight in each sock. Increased workload was achieved by increasing the rate of alternating leg flexion and extension in time with a bleep sound of increasing frequency. Twenty subjects (10 healthy volunteers, 10 patients with pulmonary arterial hypertension) performed two CMR-augmented cardiopulmonary exercise tests (CMR/CPET) using the novel exercise device and a conventional ergometer in a randomised order. Comparing peak metrics elicited on both exercise devices, there was a moderate correlation in peak oxygen consumption (VO

Indexed as

ExerciseExercise TestHealthy VolunteersHypertension, PulmonaryMagnetic Resonance ImagingAdultFemaleHumansMaleMiddle AgedReproducibility of Resultsexercise CMR devicepulmonary hypertensionsystemic sclerosis

Identifiers

PMID42830468
PMCPMC13635468

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.