Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Xia QiuDepartment of Genetics, Rutgers University, Piscataway, NJ, USA.
Xinyu HuDepartment of Genetics, Rutgers University, Piscataway, NJ, USA.
Emmanuel ZachariahRutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, Piscataway, NJ, USA.
Curtis KrierRutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, Piscataway, NJ, USA.
Ankit SaxenaRutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, Piscataway, NJ, USA.
Lei ChenSchool of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing, China.ORCID 0000-0001-7812-508X
Jiekun YangDepartment of Genetics, Rutgers University, Piscataway, NJ, USA.
Michael P VerziDepartment of Genetics, Rutgers University, Piscataway, NJ, USA. mv347@hginj.rutgers.edu.ORCID 0000-0003-4082-4330
Funding
TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Tracie Saunders · 1997 to 2026
$94.5M
Transcriptional Mechanisms of Tumor SuppressionR01CA190558 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI MICHAEL P. VERZI · 2015 to 2026
$3.6M
IMSD at Rutgers - New Brunswick (Renewal)T32GM139804 · NIGMS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Brian Daniels, JAMES H. MILLONIG · 2021 to 2026
$2.9M
Mechanisms Driving Metabolic Shifts in the Intestinal EpitheliumR01DK126446 · NIDDK · RUTGERS, THE STATE UNIV OF N.J. · PI VERZI, MICHAEL P. · 2021 to 2025
$2.1M
Mechanism of Eph-ephrin Signaling in Intestinal RegenerationF32DK145139 · NIDDK · RUTGERS, THE STATE UNIV OF N.J. · PI Ping He · 2025 to 2026
$177k
National Natural Science Foundation of China (National Science Foundation of China) 32270830, U25A2016Natural Science Foundation of Jiangsu Province (Jiangsu Provincial Natural Science Foundation) BK20230026NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA190558NIDDK NIH HHS F32 DK145139NIDDK NIH HHS R01 DK126446NIGMS NIH HHS T32 GM139804U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) 3P30CA072720-24S2U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) P30CA072720U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) P30CA072770-6852U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R01CA190558U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) F32DK145139U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R01DK126446U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) T32GM139804
6 · The paper itself
Abstract
The intestinal epithelium exhibits a remarkable capacity for regeneration following injury, yet the spatial and temporal dynamics of the damage-repair cycle remain incompletely understood. We present a spatial transcriptomics atlas of ionizing radiation-induced injury and repair in the mouse jejunum, capturing mRNA from 16,921 genes across approximately 26 million bins at 2-µm resolution in 23 biological samples spanning six days post-irradiation. Analysis reveals transcriptional patterns and niche signals undetectable by bulk or single-cell approaches, including spatially restricted interferon-target gene activation, an altered differentiation trajectory in the lower villus during early repair, two transcriptionally distinct crypt regenerative cell populations, and global transcriptional upregulation consistent with hypertranscription as a hallmark of intestinal regeneration, with evidence for hypertranscription extending to human Crohn's disease. In this work, we provide a spatiotemporal atlas of mouse intestinal regeneration at subcellular 2-µm resolution that will inform future therapeutic strategies for inflammatory bowel diseases and gastrointestinal pathologies arising from injury or cancer therapy.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
A spatial and temporal transcriptomic atlas of mouse intestinal regeneration in the jejunum. · full record | OpenQuestion