Evidence map›Paper›PMID 42829898›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026

Impact of child loss on parents' health-related quality of life: evidence from the china health and retirement longitudinal study.

Qing Su, Keshan Liu

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Qing SuSchool of Population and Health, Renmin University of China, 59 Zhongguancun St, Beijing, 100872, People's Republic of China.
Keshan LiuSchool of Population and Health, Renmin University of China, 59 Zhongguancun St, Beijing, 100872, People's Republic of China. liukeshan@ruc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGiven the profound impact of adverse life events on later-life health, this study examined how the occurrence, timing, and number of child losses were associated with trajectories of health-related quality of life (HRQoL) among middle-aged and older adults in China. It further explored potential mediating mechanisms and heterogeneity by gender and residence.

methodsUsing data from four waves (2011-2018) of the China Health and Retirement Longitudinal Study (CHARLS), this study included 13,161 individuals. HRQoL was assessed using the 36-Item Short Form Health Survey (SF-36). Linear mixed models were used to estimate longitudinal HRQoL trajectories, and the Karlson-Holm-Breen method was applied to examine potential mediating pathways.

resultsBereaved parents exhibited lower HRQoL than non-bereaved parents. The association between child loss and HRQoL varied by the timing of the loss and followed a dose-response pattern. Mediation analyses identified intergenerational support and social engagement as potential pathways. Moreover, mothers experienced a steeper decline in HRQoL over time than fathers following child loss.

conclusionThese findings suggest that child loss has a persistent and graded negative association with HRQoL, with important variation by timing and gender. The results highlight the need for targeted support and interventions to mitigate long-term health consequences among bereaved older adults.

Indexed as

BereavementHealth StatusParentsQuality of LifeAgedChinaFemaleHumansLongitudinal StudiesMaleMiddle AgedSocial SupportChild lossChinaHealth-related quality of lifeIntergenerational supportLife-course perspectiveSocial engagement

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