ArticleJournal of education and health promotion2026
Inflammatory indices and bone density in osteoporosis: A cross-sectional study.
Article in Journal of education and health promotion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundOsteoporosis and osteopenia, prevalent metabolic bone disorders, increase fracture risk, particularly in postmenopausal women. Chronic inflammation may contribute to bone loss. The association between inflammatory indices and bone mineral density (BMD) was investigated. MATERIALS AND
methodsA cross-sectional analysis involving 99 patients over the age of 40 at the Ilam Rheumatology Clinic (2019-2022) evaluated BMD using the Hologic Discovery Wi DXA and assessed blood indices with the Sysmex XN-1000. Statistical analyses, including T-tests, ANOVA, and Pearson's correlation, were conducted utilizing SPSS version 16, with significance set at
resultsAmong 99 patients (78.8% female, mean age 55.8 ± 9.7 years), the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) exhibited significant elevation in cases of osteoporosis (2.710 ± 0.610,
conclusionIncreased levels of NLR and PLR correlate with diminished BMD, suggesting their potential as cost-effective biomarkers for osteoporosis risk assessment. Monitoring these indices could enhance early diagnosis and prevention strategies in at-risk populations.
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