Evidence map›Paper›PMID 42829776›Full record

ReviewJournal of education and health promotion2026

Impact of oil fortification with iron in the prevention of anemia-A systematic review.

Ramesh Holla, Bhaskaran Unnikrishnan, Mithun Rao, Vani Verma, Chanchal Chaudhary, Vasudeva Guddattu, Jobinse Jose, Nisha Abdul Khader, Apoorva M Shankaranarayana, Arunima Biswas

Abstract readReview
In one paragraph

Review in Journal of education and health promotion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ramesh HollaDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Bhaskaran UnnikrishnanDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Mithun RaoDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Vani VermaDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Chanchal ChaudharyDepartment of Audiology and Speech Language Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Vasudeva GuddattuDepartment of Data Science, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Jobinse JoseDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Nisha Abdul KhaderDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Apoorva M ShankaranarayanaDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Arunima BiswasDepartment of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micronutrient malnutrition has gained its significant influence on public health and a role in the worldwide disease burden in recent years. Through fortification, the nutritional profile of staple foods is enhanced, making them more nutritious and beneficial for consumption. This systematic review aims to assess the impact of oil fortification with iron in anemia prevention. Electronic search through five databases and additional resources was performed by using the appropriate keywords. Out of 13,948 records that were identified, one double-blind randomized controlled trial done among Swiss women met eligibility criteria. Selected study focused on women aged between 18 and 40 years with low serum ferritin, evaluating the impact of iron-fortified low-fat margarine. This study is registered in PROSPERO (CRD42023420044). Intervention showed an increase in body iron stores with both compounds, namely, sodium iron ethylenediaminetetraacetate (NaFeEDTA) and micronized ground ferric pyrophosphate (MGFePP); however, NaFeEDTA fortification demonstrated a two to three times greater impact compared to MGFePP fortification. Findings suggest that fortification, specifically with certain iron compounds, can be a useful tactic for enhancing iron status, particularly in people with low iron stores. The only included study under this review revealed that adding iron to low-fat margarine helped boost iron levels in women with low blood iron. Findings revealed that oil fortification with NaFeEDTA showed superior efficacy over MGFePP. Further research is warranted to investigate the feasibility of fortifying edible oils with iron, exploring reasons for both potential success and challenges, thus curbing the public health issue of iron deficiency.

Indexed as

Anemiaironmargarinemicronutrient deficiencies

Identifiers

PMID42829776
PMCPMC13633798

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.