ArticleInternational medical case reports journal2026
Neonatal Gastric Perforation Temporally Associated with Nasogastric Tube Insertion: A Case Report.
Article in International medical case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Neonatal gastric perforation (NGP) is a rare but potentially life-threatening condition associated with substantial morbidity and mortality. Approximately half of reported cases are idiopathic or spontaneous, while the remainder are attributed to identifiable causes, including congenital gastric wall defects, hypoxic-ischemic injury, and iatrogenic trauma related to nasogastric tube (NGT) insertion, particularly in premature and low-birth-weight infants. Early diagnosis and prompt surgical intervention are critical for improving outcomes. We report a case of gastric perforation temporally associated with nasogastric tube insertion in a preterm, small-for-gestational-age (SGA) neonate, highlighting the diagnostic challenge of distinguishing mechanical from ischemic etiologies, together with management and preventive considerations. Case Presentation: We describe a male preterm neonate, born at 34 weeks of gestation with a birth weight of 1.5 kg (small for gestational age), who developed acute abdominal distension and respiratory distress approximately 12 hours after nasogastric tube placement for enteral feeding. Abdominal radiography revealed significant pneumoperitoneum, indicating gastrointestinal perforation. Emergency exploratory laparotomy confirmed a 1-cm full-thickness gastric perforation along the greater curvature of the stomach. The perforation was repaired surgically, and the infant subsequently recovered with comprehensive postoperative intensive care management. Conclusion: Clinicians should maintain a high index of suspicion for gastric perforation in neonates, particularly those born preterm or small for gestational age, who develop rapid abdominal distension, pneumoperitoneum, or signs of sepsis following nasogastric tube insertion. Because clinical and radiological findings alone often cannot reliably distinguish mechanical from ischemic causes, standardized insertion protocols, prompt radiological evaluation, and timely surgical intervention remain essential for improving survival and outcomes in this rare but serious condition.
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