Evidence map›Paper›PMID 42829685›Full record

ArticleRadiology advances2026

Improved visualization of malpositioned middle ear prostheses using photon-counting detector CT: a cadaver study.

Maryam Sadeghian, John C Benson, Paul J Farnsworth, John I Lane, Kevin J Treb, Karl R Khandalavala, Eric E Babajanian, Michael R Bruesewitz, Joseph R Swicklik, Fang-Shu Ou and 3 more

Abstract read
In one paragraph

Article in Radiology advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maryam SadeghianDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
John C BensonDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Paul J FarnsworthDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
John I LaneDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Kevin J TrebDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Karl R KhandalavalaDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN 55905, United States.
Eric E BabajanianDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN 55905, United States.
Michael R BruesewitzDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Joseph R SwicklikDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.
Fang-Shu OuDivision of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, United States.ORCID https://orcid.org/0000-0003-1267-8735
Cynthia H McColloughDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.ORCID https://orcid.org/0000-0002-5346-332X
Matthew L CarlsonDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN 55905, United States.
Shuai LengDepartment of Radiology, Mayo Clinic, Rochester, MN 55905, United States.ORCID https://orcid.org/0000-0002-6453-9481

Funding

High-resolution in vivo imaging of inner ear using photon-counting-detector computed tomography and artificial intelligenceR01DC022228 · NIDCD · MAYO CLINIC ROCHESTER · PI Matthew L Carlson, Shuai Leng · 2025 to 2026
$1.5M
NIDCD NIH HHS R01 DC022228
6 · The paper itself

Abstract

Background: Evaluation of middle ear prostheses requires high-resolution imaging to assess position and structural integrity. Purpose: To assess the diagnostic performance of photon-counting-detector (PCD)-CT for middle ear prosthesis imaging in cadaveric specimens. Materials and Methods: Nine different middle ear prostheses were implanted in 5 fresh-frozen whole-head specimens, both in correct anatomic position and displaced to mimic malposition. Specimens were scanned on PCD-CT (NAEOTOM Alpha, Siemens) and energy-integrating-detector (EID)-CT (SOMATOM Force, Siemens), reconstructed at 0.2 mm and 0.4 mm, respectively. Eighteen cases (9 prostheses, 2 positions) per scanner were evaluated by 2 neuroradiologists (36 readings), blinded to scanner and position, who scored prosthesis position, reader confidence, and overall image quality. Agreement with the reference standard and between readers was compared. Results: PCD-CT showed higher diagnostic confidence compared with EID-CT, while accuracy and inter-reader agreement did not demonstrate significant differences between scanners. Correct readings, PCD-CT versus EID-CT: lateral contact, 31/36 (86.1%; 95% CI, 58.3-94.4) vs 29/36 (80.6%; 95% CI, 55.6-91.7), Conclusion: PCD-CT was associated with significantly higher reader confidence and preferred image quality, without significant differences in diagnostic accuracy or inter-reader agreement. These findings suggest that PCD-CT is a promising modality for postoperative middle ear evaluations and warrants further investigations.

Indexed as

conductive hearing lossenergy-integrating detector-CTmiddle ear prosthesesphoton-counting detector-CTtemporal bone

Identifiers

PMID42829685
PMCPMC13633848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.