ArticleCureus2026
Oseltamivir-Associated Angioedema in a Patient Receiving Angiotensin-Converting Enzyme Inhibitor Therapy for Influenza A: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Influenza remains a major cause of morbidity and mortality worldwide, particularly among elderly patients with comorbidities. Oseltamivir (Tamiflu), a neuraminidase inhibitor, is the most widely prescribed antiviral therapy for influenza A and B. Although oseltamivir is associated with increased nausea and vomiting, it is generally well tolerated. On rare occasions, oseltamivir has been associated with rare hypersensitivity reactions, including angioedema. Angiotensin-converting enzyme (ACE) inhibitors are also well known to cause angioedema, sometimes years after therapy initiation. We present the case of a 73-year-old man with influenza A who developed acute lip swelling after starting oseltamivir while on long-term lisinopril therapy. Oseltamivir was discontinued, and the swelling subsided. This raised important diagnostic and therapeutic considerations in differentiating viral illness, drug reaction, and medication-induced angioedema.
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