ArticleCureus2026
Surgical Outcome of Giant Goiters: A Retrospective Observational Study.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSurgical management of giant goiters is often challenging due to distorted anatomy and proximity to vital structures in the neck.
objectiveWe aimed to evaluate the outcomes of patients operated on for giant goiters (size >10 cm) compared to non-giant ones (size ≤10 cm).
methodsThis retrospective study included 132 patients undergoing total thyroidectomy for various etiologies over 36 months (January 2022 to December 2024) in a single surgical unit of a tertiary care hospital. Clinical and surgical management details were noted from the electronic database and medical records. Data were analyzed by IBM SPSS Statistics for Windows, version 27 (IBM Corp., Armonk, NY, USA).
resultsOutcomes of 36 (27.2%) patients operated on for giant goiters were compared with 96 (72.8%) cases of non-giant goiters. Though the median duration of symptoms was significantly longer in patients with giant goiters than in those with non-giant goiters (66.0 (24.0-172.0) vs. 24.0 (8.0-69.0) months; p=0.005), the frequency of compressive symptoms was comparable between the two groups. Mean±SD size (cm) of giant goiters was 13.8±3.6, significantly higher than the size of non-giant goiters (7.2±1.6). Malignant pathology was significantly less frequent in patients with giant goiters than in those with non-giant goiters (44.4% vs. 67.8%; p = 0.039). Median duration of surgery, intraoperative blood loss, and duration of hospital stay were significantly higher for patients with giant disease. Although mean postoperative day-1 serum calcium levels were comparable between groups, the need for postoperative mechanical ventilation (16.7% vs. 1.0%; p = 0.002), tracheostomy (13.9% vs. 1.0%; p= 0.006), and postoperative recurrent laryngeal nerve palsy (13.9% vs. 4.2%; p = 0.048) was significantly higher in patients with giant disease. Other postoperative complications, including hypocalcemia rates, were similar.
conclusionGiant goiters were associated with greater intraoperative blood loss and higher frequencies of postoperative mechanical ventilation, tracheostomy, and recurrent laryngeal nerve palsy, while the incidence of hypocalcemia was comparable between the groups.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.