Evidence map›Paper›PMID 42829626›Full record

ArticleJournal of pain research2026

Artificial Intelligence Chatbots as Sources of Cancer Pain Information: A Comparative Evaluation of Quality, Transparency, and Readability.

Qianpeng Li, Shuai Zhang, Xiao Ma, Shengjie Yang

Abstract read
In one paragraph

Article in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qianpeng LiDepartment of Hematology, Weifang People's Hospital, Weifang, 261041, People's Republic of China.
Shuai ZhangDepartment of Surgery, Zhangqiu People's Hospital, Jinan, 250200, People's Republic of China.
Xiao MaDepartment of Internal Medicine, Zhangqiu People's Hospital, Jinan, 250200, People's Republic of China.ORCID 0000-0001-9654-5651
Shengjie YangPhase I Clinical Trial Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, People's Republic of China.ORCID 0000-0002-2403-7911

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the quality, transparency, educational value, and readability of cancer pain information generated by four AI chatbots and to assess whether the outputs met prespecified readability benchmarks for patient education. Methods: This online cross-sectional comparative study was conducted on July 22, 2026. Nine unmodified Google-Trends-derived cancer-pain-related queries were submitted to ChatGPT 5.5, Microsoft Copilot, Google Gemini 3.5 Flash, and Perplexity, yielding 36 responses. Two oncology clinicians independently assessed the responses using DISCERN, Ensuring Quality Information for Patients (EQIP), Journal of the American Medical Association (JAMA) benchmark criteria, and the Global Quality Score (GQS). Six established indices assessed readability. Matched model comparisons used Friedman tests with query as the repeated unit and Kendall's W as the omnibus effect size; significant quality outcomes were followed by Holm-adjusted paired Wilcoxon signed-rank tests. Results: DISCERN did not differ significantly across models (χ Conclusion: The four chatbots differed across information quality, source transparency, educational utility, and formula-based readability. Claim-level clinical accuracy and safety were not evaluated in this study and warrant separate guideline-based assessment.

Indexed as

artificial intelligencecancer painchatbotshealth informationlarge language modelspatient educationreadability

Identifiers

PMID42829626
PMCPMC13633712

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.