ArticleSurgical neurology international2026
Surgical outcomes of primary pediatric spinal cord tumors: A retrospective cohort.
Article in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Pediatric primary spinal cord tumors are rare, accounting for approximately 6% of central nervous system neoplasms. Most published data come from high-income countries (HICs) with access to early diagnosis, intraoperative monitoring, and specialized neuro-oncology units. In low- and middle-income countries (LMICs), diagnostic and therapeutic resources are limited. This report summarizes the first cohort of pediatric cases from Pakistan, highlighting surgical outcomes and systemic challenges in a resource-constrained setting. Methods: We conducted a retrospective cohort study of patients ≤18 years who underwent surgery for primary pediatric spinal tumors at a tertiary hospital in Karachi (2008-2025). Demographics, presentation, tumor location and compartment, histopathology, extent of resection, postoperative complications, adjuvant therapy status, mortality, recurrence/progression, and follow-up outcomes were extracted from records. Results: Nineteen children were included (11 female; median age, 12 years). Lower-limb weakness ( Conclusion: Surgical management of pediatric primary spinal tumors in an LMIC tertiary center was feasible, with limited documented perioperative morbidity after data correction. However, small sample size, missing event-level data, and a short median follow-up of 4 months limit interpretation of recurrence, progression-free status, and mortality. Earlier diagnosis, standardized surveillance, multidisciplinary review, rehabilitation, infection prevention, and improved access to adjuvant therapy may help strengthen care pathways in resource-constrained settings.
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