ArticleClinical interventions in aging2026
Association Between Estimated Glucose Disposal Rate and Chronic Kidney Disease in Elderly Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Zhejiang, China.
Article in Clinical interventions in aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To examine the association between estimated glucose disposal rate (eGDR) and study-defined chronic kidney disease (CKD) among elderly patients with type 2 diabetes mellitus (T2DM) in Zhejiang Province, China. Methods: This cross-sectional study included 713 elderly T2DM patients (≥60 years) from Zhejiang Province, conducted between March and November 2018 as part of the China National Diabetic Chronic Complications Study. Study-defined CKD was operationally defined as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m Results: Among 713 participants, 245 (34.36%) met the study-defined CKD criteria. Each 1-unit increase in eGDR was associated with lower odds of study-defined CKD after multivariable adjustment (OR = 0.78, 95% CI: 0.70-0.86; p < 0.001). Compared with the lowest eGDR tertile, the adjusted ORs (95% CIs) were 0.51 (0.35-0.76) for the middle tertile and 0.31 (0.20-0.48) for the highest tertile (both p < 0.001). RCS analysis demonstrated an approximately linear inverse association between eGDR and study-defined CKD (p for nonlinearity > 0.05). eGDR was inversely associated with UACR (ρ = -0.277, p < 0.001) whereas the association between eGDR and eGFR was not statistically significant. The discriminative ability of eGDR for study-defined CKD was modest (AUC = 0.65, 95% CI: 0.61-0.70). The direction of the association was generally consistent across subgroups, with no significant interactions. Conclusions: Lower eGDR was associated with a higher prevalence of study-defined CKD in elderly patients with T2DM, with an approximately linear cross-sectional association. Prospective studies are needed to establish temporality and assess whether eGDR adds information beyond established CKD assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.