Evidence map›Paper›PMID 42829513›Full record

Trial reportDepression and anxiety2026

A Randomized Controlled Trial of a Digital Stepped-Care Program to Reduce Anxiety and Depressive Symptoms Among Long-Term Care Workers With Psychological Distress: The REPICAL Study.

Leticia González-Spinoglio, Mireia Esplugues-Tormo, Iago Giné-Vázquez, Jordi Rodeiro-Boliart, Salvatore Aguilar-Ortiz, Jose Luis Ayuso-Mateos, Kerry R McGreevy, Roberto Mediavilla, Rinske Roos, Marit Sijbrandij and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Depression and anxiety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Leticia González-SpinoglioInstitut de Recerca Sant Joan de Déu (IRSJD) Parc Sanitari Sant Joan de Déu Sant Boi de Llobregat (Barcelona) Spain pssjd.org.ORCID https://orcid.org/0000-0001-6694-9815
Mireia Esplugues-TormoInstitut de Recerca Sant Joan de Déu (IRSJD) Parc Sanitari Sant Joan de Déu Sant Boi de Llobregat (Barcelona) Spain pssjd.org.ORCID https://orcid.org/0009-0004-0057-4685
Iago Giné-VázquezInstitut de Recerca Sant Joan de Déu (IRSJD) Parc Sanitari Sant Joan de Déu Sant Boi de Llobregat (Barcelona) Spain pssjd.org.ORCID https://orcid.org/0000-0002-6725-2638
Jordi Rodeiro-BoliartInstitut de Recerca Sant Joan de Déu (IRSJD) Parc Sanitari Sant Joan de Déu Sant Boi de Llobregat (Barcelona) Spain pssjd.org.ORCID https://orcid.org/0000-0001-5349-8269
Salvatore Aguilar-OrtizInstitut de Recerca Sant Joan de Déu (IRSJD) Parc Sanitari Sant Joan de Déu Sant Boi de Llobregat (Barcelona) Spain pssjd.org.ORCID https://orcid.org/0000-0003-2978-7778
Jose Luis Ayuso-MateosCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) Instituto de Salud Carlos III Madrid Spain isciii.es.ORCID https://orcid.org/0000-0002-7544-826X
Kerry R McGreevyCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) Instituto de Salud Carlos III Madrid Spain isciii.es.ORCID https://orcid.org/0000-0002-5509-4820
Roberto MediavillaCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) Instituto de Salud Carlos III Madrid Spain isciii.es.ORCID https://orcid.org/0000-0001-6411-9439
Rinske RoosDepartment of Clinical Neuro- and Developmental Psychology WHO Collaborating Center for Research and Dissemination of Psychological Interventions Amsterdam Public Health Institute Vrije Universiteit Amsterdam Amsterdam Netherlands vu.nl.ORCID https://orcid.org/0009-0000-2245-1169
Marit SijbrandijDepartment of Clinical Neuro- and Developmental Psychology WHO Collaborating Center for Research and Dissemination of Psychological Interventions Amsterdam Public Health Institute Vrije Universiteit Amsterdam Amsterdam Netherlands vu.nl.ORCID https://orcid.org/0000-0001-5430-9810
Anke B WitteveenDepartment of Clinical Neuro- and Developmental Psychology WHO Collaborating Center for Research and Dissemination of Psychological Interventions Amsterdam Public Health Institute Vrije Universiteit Amsterdam Amsterdam Netherlands vu.nl.ORCID https://orcid.org/0000-0002-9636-7522
Josep Maria HaroInstitut de Recerca Sant Joan de Déu (IRSJD) Parc Sanitari Sant Joan de Déu Sant Boi de Llobregat (Barcelona) Spain pssjd.org.ORCID https://orcid.org/0000-0002-3984-277X
Mireia Felez-NobregaInstitut de Recerca Sant Joan de Déu (IRSJD) Parc Sanitari Sant Joan de Déu Sant Boi de Llobregat (Barcelona) Spain pssjd.org.ORCID https://orcid.org/0000-0002-3484-4119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Long-term care workers (LTCWs), encompassing those in long-term care facilities and home-care settings, constitute a particularly vulnerable population to psychological distress. This study aimed to evaluate the effectiveness of a digital stepped-care program, adapted from two World Health Organization (WHO) psychological interventions-Doing What Matters in Times of Stress (DWM) and Problem Management Plus (PM+)-in reducing anxiety and depressive symptoms among LTCWs. Methods: A parallel-group randomized controlled trial was conducted. Participants were LTCWs from Catalonia (Spain) experiencing psychological distress (Kessler Psychological Distress Scale, K10 ≥ 16). All participants received Psychological First Aid (PFA), and those in the intervention group subsequently received the digital stepped-care program: DWM as step 1, and if psychological distress persisted (K10 ≥ 16), PM + as step 2. The primary outcome was the between-group difference in self-reported depressive and anxiety symptoms at week 21 (2-month post-program follow-up), measured using the Patient Health Questionnaire-Anxiety and Depression Scale (PHQ-ADS). Secondary outcomes included depressive and anxiety symptoms measured separately, post-traumatic stress disorder (PTSD) symptoms, and health-related quality of life (HR-QoL; measured using PHQ-9, 7-item Generalized Anxiety Disorder [GAD-7] scale, PCL-5, and EuroQol 5-dimensional descriptive system-5-level [EQ-5D-5L], respectively). Results: Between October 2022 and May 2024, 165 participants were randomized (intervention: Conclusions: This study provides evidence supporting the effectiveness of a digital and scalable stepped-care program to support LTCWs' mental health. These robust findings may inform occupational and public health strategies for supporting LTCWs' experiencing psychological distress.

Indexed as

AnxietyDepressionHealth PersonnelLong-Term CarePsychological DistressAdultDigital HealthFemaleHumansMaleMiddle AgedSpaindepressiondigital mental health interventionseHealthhealth-related quality of lifehome-care workersmental healthpost-traumatic stress disorderscalable interventionstelemedicine

Identifiers

PMID42829513
PMCPMC13633456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.