Evidence map›Paper›PMID 42829395›Full record

ReviewJournal of human hypertension2026

Effect of interventions for stress management on blood pressure changes in healthy adults: a systematic review and meta-analysis.

Juna Kamijima, Ai Ikeda, Hadrien Charvat, Tetsuya Ohira, Isao Muraki, Tomonori Okamura, Shiho Sato, Moemi Miura, Qisheng Li, Shiori Ikeda and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of human hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juna KamijimaDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0009-0004-0215-289X
Ai IkedaDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan. a-noda@juntendo.ac.jp.ORCID http://orcid.org/0000-0002-6261-0870
Hadrien CharvatDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-3624-1394
Tetsuya OhiraDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Isao MurakiDepartment of Public Health Medicine, Institute of Medicine, and Health Services Research and Development Center, University of Tsukuba, Tsukuba, Japan.ORCID http://orcid.org/0000-0003-0058-7721
Tomonori OkamuraDepartment of Preventive Medicine and Public Health, Keio University School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-0488-0351
Shiho SatoDepartment of Epidemiology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Moemi MiuraDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Qisheng LiDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0002-7487-542X
Shiori IkedaDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0009-0002-4304-0398
Kazumasa YamagishiDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-3301-5519
Takeshi TanigawaDepartment of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID http://orcid.org/0000-0003-3373-4492

Funding

Japan Agency for Medical Research and Development (AMED) JP22rea522104Japan Agency for Medical Research and Development (AMED) JP25gm1910012
6 · The paper itself

Abstract

Non-pharmacological therapy or lifestyle modification is recommended as a first-line approach to hypertension management. Chronic stress is a modifiable risk factor of hypertension through behavioral change. However, no prior studies have conducted a meta-analysis of stress management aimed at the primary prevention of hypertension in normotensive general population. We systematically searched PubMed, Web of Science, Scopus, and Cochrane library for eligible trials, limited to English-language articles published up to October 2025. Studies involving healthy adults without hypertension that used interventions for stress management and reported blood pressure outcomes were included. Effect sizes were calculated as between-group mean differences in systolic and diastolic blood pressures change, and were pooled using a random-effects model. Twenty-two randomized controlled trials with a maximal total sample of 3089 individuals were included in the meta-analysis. Among the different types of intervention considered, a consistent reduction in systolic blood pressure (between-group mean difference (mmHg) [95% confidence interval]) compared with the control was found for mind-body exercise (-2.17 [-3.29, -1.05]); for meditation (-1.49 [-2.67, -0.31]); and for relaxation (-4.76 [-8.48, -1.04]). Similarly, reductions in diastolic blood pressure were found with values of -1.69 [-2.81, -0.56]; -1.00 [-1.84, -0.15]; and -1.71 [-3.99, 0.56], respectively. Interventions for stress management may lower systolic and diastolic blood pressures in normotensive general population. It is possible that stress management contributes to reduce future cardiovascular risk.

Identifiers

PMID42829395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.