Evidence map›Paper›PMID 42828698›Full record

ReviewCurrent cardiology reports2026

Eosinophilia and the Heart: Evolving Concepts.

Jan Habasko, Petr Kuchynka, Mayara Elisa Bonatto, Tomas Palecek

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jan Habasko2nd Department of Medicine - Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 499/2, Prague, 12808, Czech Republic.
Petr Kuchynka2nd Department of Medicine - Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 499/2, Prague, 12808, Czech Republic. petr.kuchynka@vfn.cz.
Mayara Elisa BonattoInstitute of Rheumatology, Na Slupi 4, Prague, 128 00, Czech Republic.
Tomas Palecek2nd Department of Medicine - Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 499/2, Prague, 12808, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review summarises recent advances in cardiac involvement in eosinophilia, with particular emphasis on pathophysiology, diagnostic challenges and therapeutic options. RECENT

findingsUp to 43% of patients with histologically proven eosinophilic myocarditis (EM) have no evidence of peripheral blood eosinophilia. Aberrations in the interleukin-5 pathway are central to the pathophysiology of EM. In addition, other contributing factors for specific aetiologies are being recognised, such as susceptibility loci GPA33 and IRF1/IL5 in patients with ANCA-negative eosinophilic granulomatosis with polyangiitis. There is growing evidence for interleukin-5 pathway inhibition in disease management. EM carries a high mortality risk and thus, early identification of these patients, multidisciplinary collaboration and early initiation of targeted therapy are of utmost importance. Future studies are needed to investigate other therapeutic options, including long-acting anti-interleukin-5 inhibitors.

Indexed as

EosinophiliaMyocarditisHumansInterleukin-5Interleukin-5Cardiac magnetic resonanceEndomyocardial biopsyEosinophiliaEosinophilic cardiac involvementEosinophilic myocarditis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.