Evidence map›Paper›PMID 42828675›Full record

ArticleJournal of ultrasound2026

Ultrasound features of visceral cat scratch disease: a rare case of granulomatous hepatosplenic bartonellosis in an immunocompetent patient.

Giorgia Russo, Elisabetta Biasini, Gabriele Missale

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Article in Journal of ultrasound, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giorgia RussoInfectious Diseases Unit, Department of Medicine and Surgery, University Hospital of Parma, University of Parma, Parma, Italy. giorgia.russo@unipr.it.ORCID http://orcid.org/0009-0001-1262-123X
Elisabetta BiasiniInfectious Diseases Unit, Department of Medicine and Surgery, University Hospital of Parma, University of Parma, Parma, Italy.
Gabriele MissaleInfectious Diseases Unit, Department of Medicine and Surgery, University Hospital of Parma, University of Parma, Parma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the pivotal role of conventional B-mode and contrast-enhanced ultrasound (CEUS) in identifying and characterizing rare visceral manifestations of Bartonella henselae infection in an immunocompetent individual. CASE REPORT: A 67-year-old immunocompetent female presented with a diffuse maculopapular exanthema, fever, and left inguinal lymphadenopathy following a cat scratch. Conventional ultrasound revealed multiple subcentimetric hypoechoic areas in both hepatic lobes and the spleen, along with a necrotic-colliquative nodal mass in the left Scarpa's triangle. CEUS demonstrated an inflammatory/necrotic perfusion pattern characterized by absence of contrast enhancement, appearing as avascular, non-enhancing necrotic cores suggestive of granulomatous lesions. The clinical suspicion was confirmed by positive Bartonella henselae serology. Clinical resolution was achieved after a 1-month course of doxycycline.

conclusionsVisceral cat scratch disease should be considered in the differential diagnosis of multiple hepatosplenic lesions even in fully immunocompetent hosts. Multiparametric ultrasound, particularly CEUS, represents an essential, non-invasive standard tool for early detection, definitive characterization, and radiation-free therapeutic monitoring.

Indexed as

Bartonella henselaeCat scratch diseaseContrast-enhanced ultrasound (CEUS)Hepatosplenic granulomaMultiparametric ultrasound

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.