Evidence map›Paper›PMID 42828613›Full record

ArticleJapanese journal of ophthalmology2026

Visual and OCT outcomes in epiretinal membrane foveoschisis with and without lamellar macular hole-related diseases.

Tatsuho Tomiyama, Noriko Kubota, Yosai Mori, Kazunori Miyata, Tomoyuki Kunishige, Yuji Nakano, Hitoshi Goto, Fumiki Okamoto

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Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tatsuho TomiyamaDepartment of Ophthalmology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Noriko KubotaDepartment of Ophthalmology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan. oishinoriko@nms.ac.jp.
Yosai MoriMiyata Eye Hospital, Miyazaki, Japan.
Kazunori MiyataMiyata Eye Hospital, Miyazaki, Japan.
Tomoyuki KunishigeDepartment of Ophthalmology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Yuji NakanoDepartment of Ophthalmology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Hitoshi GotoDepartment of Ophthalmology, Nippon Medical School Tama Nagayama, Tokyo, Japan.
Fumiki OkamotoDepartment of Ophthalmology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate changes in visual acuity and optical coherence tomography (OCT) findings after vitrectomy for epiretinal membrane foveoschisis (ERM-FS), and to compare visual and anatomical outcomes among eyes with ERM-FS alone, ERM-FS associated with macular pseudohole (MPH), and ERM-FS associated with lamellar macular hole (LMH). STUDY

designRetrospective observational study

methodsThis study included eyes with ERM-FS that underwent vitrectomy between April 2020 and November 2023 and were followed for at least 6 months. Eyes with ERM-FS alone were classified as the ERM-FS group, those with concomitant MPH as the ERM-FS+MPH group, and those with concomitant LMH as the ERM-FS+LMH group. Best-corrected visual acuity (BCVA) and OCT findings were evaluated before surgery and at 1, 3, and 6 months. OCT assessments included foveoschisis, inner retinal cysts, epiretinal proliferation (EP), and ellipsoid zone (EZ) disruption.

resultsFifty-nine eyes were included. BCVA improved significantly in the overall cohort and in each group. Patients in the ERM-FS+LMH group tended to have poorer visual outcomes than those in the ERM-FS and ERM-FS+MPH groups. Schisis gradually decreased after surgery in all groups. The ERM-FS+LMH group showed a higher prevalence of EP than the other groups and a significantly higher frequency of EZ disruption than the ERM-FS group. In the ERM-FS+LMH group, postoperative BCVA was associated with preoperative EZ disruption. Multivariate analysis identified preoperative BCVA as an independent predictor of postoperative BCVA.

conclusionsVitrectomy for ERM-FS improved visual acuity and retinal morphology in all groups. However, eyes with concomitant LMH tended to have poorer postoperative visual outcomes.

Indexed as

Epiretinal membrane foveoschisisLamellar macular holeMacular pseudoholeOptical coherence tomographyVitrectomy

Identifiers

PMID42828613

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.