Evidence map›Paper›PMID 42828582›Full record

ArticleJournal of bone and mineral metabolism2026

Treatment-dependent association between sarcopenia and ADL at discharge after osteoporotic vertebral fractures.

Shunya Mimatsu, Sho Nishida, Shingo Koyama, Iwao Kojima, Yusuke Terao, Shu Tanaka, Kosaku Katsumata, Ryosuke Kita, Keigo Sato, Yushin Yamamoto and 3 more

Abstract read
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In one paragraph

Article in Journal of bone and mineral metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shunya MimatsuDepartment of Rehabilitation, Moriya Daiichi General Hospital, 1-17 Matsumaedai, Moriya-City, Ibaraki, 302-0102, Japan. mimashun7@gmail.com.ORCID http://orcid.org/0009-0000-9849-0770
Sho NishidaGraduate School of Comprehensive Human Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-Ku, Tokyo, 112-0012, Japan.
Shingo KoyamaFaculty of Health Sciences, Tsukuba University of Technology, 4-12-7 Kasuga, Tsukuba-City, Ibaraki, 305-8521, Japan.
Iwao KojimaGraduate School of Comprehensive Human Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-Ku, Tokyo, 112-0012, Japan.
Yusuke TeraoDepartment of Rehabilitation Medicine, The Jikei University School of Medicine Hospital, 3-25-8 Nishi-Shimbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Shu TanakaMajor of Physical Therapy, Department of Rehabilitation, School of Health Sciences, Tokyo University of Technology, 5-23-22 Nishikamata, Ota-Ku, Tokyo, 144-8535, Japan.
Kosaku KatsumataGraduate School of Comprehensive Human Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-Ku, Tokyo, 112-0012, Japan.
Ryosuke KitaGraduate School of Comprehensive Human Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-Ku, Tokyo, 112-0012, Japan.
Keigo SatoGraduate School of Comprehensive Human Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-Ku, Tokyo, 112-0012, Japan.
Yushin YamamotoGraduate School of Comprehensive Human Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-Ku, Tokyo, 112-0012, Japan.
Daisuke FukayaDepartment of Rehabilitation, Moriya Daiichi General Hospital, 1-17 Matsumaedai, Moriya-City, Ibaraki, 302-0102, Japan.
Itsuo ShiinaDepartment of Orthopaedic Surgery, Moriya Daiichi General Hospital, 1-17 Matsumaedai, Moriya-City, Ibaraki, 302-0102, Japan.
Minoru YamadaFaculty of Human Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-Ku, Tokyo, 112-0012, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSarcopenia has been associated with lower activities of daily living (ADL). This study investigated whether sarcopenia at admission is associated with ADL at discharge in patients with osteoporotic vertebral fractures (OVF) and whether this differs by treatment (conservative or balloon kyphoplasty, BKP). MATERIALS AND

methodsThis prospective cohort study included 78 patients with OVF (76.8% female; mean age 83.0 ± 6.7 years). Sarcopenia was defined according to the 2019 Asian Working Group for Sarcopenia criteria, requiring low skeletal muscle mass and low handgrip strength. The outcome was ADL at discharge. Multivariate regression analyses were performed after adjusting for age, sex, mini-mental state examination (MMSE), functional independence measure (FIM-M) at admission, and geriatric nutritional risk index (GNRI). An interaction term (sarcopenia × treatment) was included to examine treatment-dependent associations.

resultsMultivariate analysis revealed a significant association between sarcopenia at admission and lower FIM-M at discharge (B = - 11.77, β = - 0.36, 95% CI = - 20.47 to - 3.07, P = 0.009). A significant interaction between sarcopenia and treatment was also detected (B = 5.81, β = 0.40, 95% CI = 0.02 to 11.60, P = 0.049), indicating that the association between sarcopenia and FIM-M at discharge differed with treatment modality.

conclusionSarcopenia at admission correlated with ADL at discharge in patients with OVF. This association was modified by treatment modality, with the negative association attenuated in patients undergoing BKP.

Indexed as

Activities of daily livingBalloon kyphoplastyConservative treatmentOsteoporotic vertebral fractureSarcopenia

Identifiers

PMID42828582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.