Evidence map›Paper›PMID 42828502›Full record

Trial reportJournal of the International Society of Sports Nutrition2026

Effects of a chickpea protein hydrolysate on exercise-induced biomarkers of muscle damage and inflammation in federated road cyclists.

Jesús García-Durán, Antonio J Sánchez-Oliver, Noelia M Rodríguez-Martín, María-Soledad Fernández-Pachón, Justo Pedroche, Francisco Millán, José Antonio González-Jurado

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jesús García-DuránFaculty of Sports Science, Pablo de Olavide University, Seville, Spain.
Antonio J Sánchez-OliverDepartamento de Motricidad Humana y Rendimiento Deportivo, Universidad de Sevilla, Seville, Spain.ORCID 0000-0001-9022-6043
Noelia M Rodríguez-MartínGroup of Plant Proteins, Instituto de la Grasa-CSIC, Seville, Spain.ORCID 0000-0003-4737-2330
María-Soledad Fernández-PachónArea of Nutrition and Food Sciences, Department of Molecular Biology and Biochemistry Engineering, Universidad Pablo de Olavide, Seville, Spain.ORCID 0000-0002-9524-298X
Justo PedrocheGroup of Plant Proteins, Instituto de la Grasa-CSIC, Seville, Spain.ORCID 0000-0002-2562-3779
Francisco MillánGroup of Plant Proteins, Instituto de la Grasa-CSIC, Seville, Spain.ORCID 0000-0001-6309-7629
José Antonio González-JuradoFaculty of Sports Science, Pablo de Olavide University, Seville, Spain.ORCID 0000-0003-2222-6089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis randomized, double-blind, placebo-controlled trial examined the effects of a chickpea protein hydrolysate (CPH) on biomarkers associated with exercise-induced muscle damage and inflammation in federated male road cyclists.

methodsTwenty-four participants completed a 14-day intervention receiving either 12 g/day of chickpea protein hydrolysate (EXP) or a placebo (PLA) following training sessions. The selected dose was based on previous studies demonstrating antioxidant and immunomodulatory bioactive properties of the hydrolysate. Nutritional intake and training were registered. Body composition and biochemical markers of muscle damage and inflammation were assessed before and after the study.

resultsNo significant differences were observed in body composition, training load, or dietary intake between groups, indicating controlled experimental conditions. However, between-group analyses of change scores revealed significant differences for lactate dehydrogenase (LDH;

conclusionsIn trained cyclists with high habitual protein intakes, 14 days of CPH supplementation did not alter body composition but was associated with favorable changes in selected biomarkers related to exercise-induced inflammation and cellular stress compared with placebo. Given the short intervention period and the absence of direct assessments of recovery or performance, these findings should be interpreted as short-term biochemical responses. Further studies are required to determine their physiological relevance and whether these biomarker changes translate into meaningful improvements in recovery, training adaptation, or athletic performance.

Indexed as

BicyclingCicerInflammationMuscle, SkeletalProtein HydrolysatesAdultBiomarkersBody CompositionC-Reactive ProteinCreatine KinaseDietary SupplementsDouble-Blind MethodHumansL-Lactate DehydrogenaseMaleSports Nutritional Physiological PhenomenaBiomarkersC-Reactive ProteinCreatine KinaseL-Lactate DehydrogenaseProtein HydrolysatesRecovery, endurance athletes, cycling, plant-based protein, chickpea protein

Identifiers

PMID42828502
PMCPMC13644453

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.