Glycopolymer-based nanofibers with tunable polyelectrolyte content for modulating cellular interactions and drug delivery.

Hannah Schnicke, Harvey K MacKenzie, J Diego Garcia-Hernandez, Steven T G Street, Zachary M Hudson, Ian Manners

Abstract read

In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hannah SchnickeDepartment of Chemistry, University of Victoria 3800 Finnerty Rd Victoria British Columbia V8P 5C2 Canada.ORCID https://orcid.org/0009-0006-8054-5853

Harvey K MacKenzieDepartment of Chemistry, University of Victoria 3800 Finnerty Rd Victoria British Columbia V8P 5C2 Canada.ORCID https://orcid.org/0000-0003-2078-6998

J Diego Garcia-HernandezDepartment of Chemistry, University of Victoria 3800 Finnerty Rd Victoria British Columbia V8P 5C2 Canada.ORCID https://orcid.org/0000-0001-6343-5659

Steven T G StreetDepartment of Chemistry, University of Victoria 3800 Finnerty Rd Victoria British Columbia V8P 5C2 Canada.ORCID https://orcid.org/0000-0002-7635-8733

Zachary M HudsonDepartment of Chemistry, University of British Columbia 2023 Main Mall Vancouver British Columbia V6T 1Z1 Canada zhudson@chem.ubc.ca.ORCID https://orcid.org/0000-0002-8033-4136

Ian MannersDepartment of Chemistry, University of Victoria 3800 Finnerty Rd Victoria British Columbia V8P 5C2 Canada.ORCID https://orcid.org/0000-0002-3794-967X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymer-based nanoparticles are emerging as a promising class of nanomedicines, yet are typically limited to spherical morphologies with limited control over particle size. As nanoparticle morphology, size, dispersity and surface chemistry dictate their biological performance, developing nanoparticles with precise control over these parameters is essential for the design of next-generation nanomedicines. Here, we report one-dimensional triblock nanofibers with a dual-functional corona, that combine the minimal cytotoxicity of a polyfructose glycopolymer and the improved cellular interaction of polyamine polyelectrolytes. Living crystallization-driven self-assembly enables precise length and dispersity control of poly(fluorene trimethylene carbonate)-

Identifiers

PMID42828347

DOI10.1039/d6sc06330f

PMCPMC13632826

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.