Evidence map›Paper›PMID 42828327›Full record

ReviewCureus2026

Exploring the Effect of Nutrition on Fetal Development in Pregnant Patients With Inflammatory Gut Diseases: A Scoping Review.

Zena K Moody, Anitha T Joseph, Ravdeep Gill, Rajin Persaud, Adriana Gurreri, Christo Manikkuttiyil, Adina Ahmed, Shreya Golakoti, Sarah Villamil, Ravi Ghotra and 1 more

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zena K MoodyCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Miami, USA.
Anitha T JosephCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Ravdeep GillCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Rajin PersaudCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Adriana GurreriCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Christo ManikkuttiyilCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Adina AhmedCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Shreya GolakotiCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.
Sarah VillamilCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Ravi GhotraCollege of Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Miami, USA.
Ioana ScripaNutrition, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory gut diseases (IGDs) are increasing in prevalence and pose unique challenges during pregnancy. Poorly controlled IGDs in pregnant women are linked to adverse fetal outcomes such as low birth weight, preterm birth, and impaired gut microbiome development. Nutritional deficiencies, particularly in magnesium, folate, and vitamin B12, exacerbate these risks due to both inadequate intake and malabsorption. This scoping review aimed to evaluate the role of nutrition in fetal development among pregnant women with IGDs, highlighting dietary strategies that may enhance maternal gastrointestinal health and optimize fetal outcomes. This study was designed as a scoping review to examine the relationship between IGDs, pregnancy, and nutrition. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping review (PRISMA-ScR) guidelines, a search was conducted for peer-reviewed literature using the databases Embase, Web of Science, Ovid MEDLINE, and CINAHL. The search was restricted to studies published in English within the last ten years and that focused on pregnant or postpartum patients and fetuses in the context of nutrition and IGDs. The search strategy used predefined terms in multiple combinations with Boolean operators: "inflammatory bowel disease", "pregnancy", "fetus development", "nutritional deficiency", "diet restriction", and "vitamin supplementation". The search identified 1,589 records, of which 728 remained after duplicate removal. Following title and abstract screening, 103 full-text reports were sought for retrieval, 98 were assessed for eligibility, and five studies met the final inclusion criteria. The included studies suggest that multidisciplinary antenatal care, maintenance of disease remission, and attention to maternal nutritional status may support favorable maternal and neonatal outcomes. However, the available evidence is limited, consists primarily of observational studies, and no included study directly evaluated nutritional interventions and fetal outcomes. Research on fetal outcomes remains limited and warrants future investigations exploring long-term fetal outcomes, the impact of maternal nutritional deficiencies, and dietary interventions to improve treatment protocols. Advancements in this research can ultimately improve maternal and neonatal outcomes in IGD-affected pregnancies.

Indexed as

diet restrictionfetus developmentinflammatory bowel diseasenutritional deficiencypregnancyvitamin supplementation

Identifiers

PMID42828327
PMCPMC13632571

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.