Evidence map›Paper›PMID 42828308›Full record

ArticleFrontiers in medicine2026

Essential oil massage and incident chronic kidney disease-associated pruritus in maintenance hemodialysis patients without baseline pruritus: a prospective non-concurrent before-and-after study.

Xian Shen, Ting Shen, Jing Luo, Peng Fu, Mengru Liu, Congcong Cao, Hao Wu, Jing Cui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xian Shen *Shidong Hospital, University of Shanghai for Science and Technology, Shanghai, China.
Ting Shen *Shidong Hospital, University of Shanghai for Science and Technology, Shanghai, China.
Jing LuoShidong Hospital, University of Shanghai for Science and Technology, Shanghai, China.
Peng FuShidong Hospital, University of Shanghai for Science and Technology, Shanghai, China.
Mengru LiuSchool of Nursing, Bengbu Medical College, Bengbu, China.
Congcong CaoSchool of Nursing, Bengbu Medical College, Bengbu, China.
Hao WuShidong Hospital, University of Shanghai for Science and Technology, Shanghai, China.
Jing CuiShidong Hospital, University of Shanghai for Science and Technology, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare the incidence of chronic kidney disease-associated pruritus (CKD-aP) between two consecutive care phases among maintenance hemodialysis patients without pruritus at baseline, following the addition of essential oil massage to standardized hemodialysis care and basic skin care. Methods: This single-center, prospective, non-concurrent before-and-after controlled study enrolled 87 maintenance hemodialysis patients from January to December 2024. Patients in the control phase ( Results: No baseline characteristic differed statistically between the two phases; however, SMDs indicated mild imbalance in several variables. During follow-up, the incidence of pruritus was significantly lower in the intervention group than in the control group (31.8% vs. 65.1%, Conclusion: The intervention phase showed a lower observed incidence of new-onset CKD-aP and less topical ointment use among maintenance hemodialysis patients without pruritus at baseline. However, because intervention exposure was completely aligned with calendar period, this study cannot distinguish an intervention effect from a seasonal effect, and the observed difference should not be interpreted as evidence of preventive benefit. Findings regarding pruritus severity among patients who developed pruritus during follow-up were exploratory.

Indexed as

chronic kidney disease-associated pruritusessential oil massagehemodialysisnon-pharmacological interventionsymptom management

Identifiers

PMID42828308
PMCPMC13632480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.