Evidence map›Paper›PMID 42828303›Full record

ArticleiScience2026

Monotropein mitigates atherosclerotic plaque vulnerability through circ_0140736/miR-495/SIRPα-mediated efferocytosis.

Ying Liu, Zuoli Wu, Bingyu Huang, Weihao Ye, Shang Xu, Wenbo He, Yining Lan, Chao Xiao, Chao Qin, Wen Gao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ying LiuDepartment of Rehabilitation Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Zuoli WuDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Bingyu HuangDepartment of Rehabilitation Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Weihao YeDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Shang XuDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Wenbo HeDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Yining LanDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Chao XiaoDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Chao QinDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Wen GaoDepartment of Neurology, Liuzhou People's Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi 545000, China.
Ziming YeDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efferocytosis is a biological process in which phagocytic cells engulf and degrade senescent, damaged, or dead cells to prevent secondary necrosis and inflammation. This process is implicated in various diseases, including atherosclerosis (AS). Enhancing efferocytosis efficiency may offer a promising therapeutic strategy for managing AS. Consequently, increasing attention is being paid to pharmacological agents that can promote efferocytosis. Monotropein (MON), the predominant iridoid glycoside in

Indexed as

atherosclerosiscirc_0140736efferocytosismonotropeinSIRPα

Identifiers

PMID42828303
PMCPMC13632206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.