Evidence map›Paper›PMID 42828227›Full record

ArticleFrontiers in radiology2026

The application of deep neural networks to the detection of lumbar hernias: results from the approaches based on convolutional networks and transformers.

António Fernandes, João Pedro Mazuco Rodriguez, Susana Moleirinho, Irina Trofimenko, Ekaterina Guseva, Alexander Martinovich, Ilzane Maria de Oliveira Morais, Louise Bisolo, Luís Mendes Gomes, José Machado

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Article in Frontiers in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

António FernandesSliceD Group Research Center, Lisbon, Portugal.
João Pedro Mazuco RodriguezSliceD Group Research Center, Lisbon, Portugal.
Susana MoleirinhoSliceD Group Research Center, Lisbon, Portugal.
Irina TrofimenkoSliceD Group Research Center, Lisbon, Portugal.
Ekaterina GusevaSliceD Group Research Center, Lisbon, Portugal.
Alexander MartinovichSliceD Group Research Center, Lisbon, Portugal.
Ilzane Maria de Oliveira MoraisSliceD Group Research Center, Lisbon, Portugal.
Louise BisoloSliceD Group Research Center, Lisbon, Portugal.
Luís Mendes GomesALGORITMI, LASI, Universidade do Minho, Braga, Portugal.
José MachadoALGORITMI, LASI, Universidade do Minho, Braga, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The increasing demand for lumbar spine MRI exams, combined with radiologist shortages, has underscored the need for automated tools to assist in diagnosing degenerative spinal conditions. Despite the proliferation of AI tools in radiology, no CE or FDA-approved applications currently focus on pathologies in the lumbar spine. This study aimed to develop a pipeline for automatic identification of intervertebral disc herniation, contributing to more efficient clinical decision-making. Methods: A dataset of 484 lumbar spine MRI examinations acquired from four manufacturers was used to develop a multi-stage deep learning pipeline. An overview of the proposed automated lumbar spine MRI analysis framework is presented, illustrating the main stages of the pipeline including dataset preparation, disc segmentation, feature extraction, and classification. A subset of 165 studies (5,200 sagittal slices) was manually annotated by radiologists and used for training and validation of vertebrae and intervertebral disc segmentation models, including U-Net, DeepLabV3+, and MA-Net with EfficientNet-B2 backbones. Anatomically informed post-processing was applied to assign disc-level labels and extract disc-centered volumes. Disc-level binary classification (herniated vs. non-herniated) was then performed using 3D patch-based models, including ResNet, SENet, EfficientNet-B2, and Vision Transformer (ViT) architectures, with all dataset splits performed at the patient level. Results: The best segmentation performance was achieved by MA-Net with EfficientNet-B2, yielding a Dice Score of 0.898 for three-class segmentation (background, vertebrae, discs). For classification, the evaluated models achieved F1-scores between 0.66 and 0.73. The best performance was obtained with a ResNet18-based model, indicating that once anatomical localization and disc extraction are addressed by the segmentation stage, lower-capacity architectures can be effective for binary classification. The simplified three-class segmentation improved model robustness, and post-processing enabled disc-level precision essential for downstream classification, which achieved consistent performance across models under the available data regime. Conclusion: The proposed AI pipeline successfully automates the identification of lumbar disc herniation in MRI exams. This approach has the potential to enhance diagnostic efficiency, reduce radiologist workload, and improve reproducibility in identifying disc pathologies. While limited by sample size and class imbalance, the methodology lays a strong foundation for scalable annotation and integration of AI in routine spinal diagnostics.

Indexed as

3D classification modelsdeep learningdisc herniationlumbar spine MRImedical image segmentationradiology automation

Identifiers

PMID42828227
PMCPMC13632042

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.