ArticleCureus2026
Arthroscopic Rotator Cuff Repair With Collagen Patch Augmentation: An In Vivo Examination of Biologic and Biomechanical Patches.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of patch augmentation in the setting of large-to-massive rotator cuff repairs and poor tissue quality may reinforce native tissue and add structural integrity, potentially decreasing retear rates. Many patches are currently marketed for this use, with research focusing primarily on easily observable surgical outcomes, including range of motion, pain, and functionality. These case reports investigate the use of two such patches, Regeneten (Smith+Nephew, Andover, MA, USA) and BioBrace ( CONMED, New Haven, CT, USA), observed at subsequent revision surgeries; this in vivo observation provides insight into the cellular effects of these patches, namely, the extent of healing and tissue proliferation. In case 1, Patient A received a Regeneten patch during initial repair; upon revision nine months later, staple fragments were found floating in the joint space, with no evidence of the previously placed patch except for bone anchors. In case 2, Patient B received a BioBrace patch during initial repair; upon revision five months later, the patch was found to be intact and well-integrated, with evidence of cellular overgrowth and neovascularity. These two cases, each a single point-in-time evaluation of a prior rotator cuff repair with patch augmentation, raise questions regarding a potential difference in the bioinductive properties of the two patches. Further large-scale studies are warranted to investigate the different bioinductive qualities of the patches and their role in the cellular healing process, as well as their unique complication risks.
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