Evidence map›Paper›PMID 42827943›Full record

ArticleCurrent research in microbial sciences2026

Gut microbial allies and adversaries in SARS-CoV-2 infection.

Veronica Tolosa-Enguis, María Leonor Fernández-Murga, Alfonso Benitez-Páez, Carlos Francés-Cuesta, Javier Garde-Noguera, Antonio Llombart-Cusscac, Gara Verónica Molina-Mendoza, Ana Isabel Aviles-Alia, Ron Geller, Laura Mendoza-García and 3 more

Abstract read
In one paragraph

Article in Current research in microbial sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Veronica Tolosa-EnguisInstitute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Paterna-Valencia, Spain.
María Leonor Fernández-MurgaMolecular and Clinical Oncology Laboratory (OMC), Hospital Arnau de Vilanova, Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO), Valencia, Spain.
Alfonso Benitez-PáezInstitute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Paterna-Valencia, Spain.
Carlos Francés-CuestaInstitute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Paterna-Valencia, Spain.
Javier Garde-NogueraMolecular and Clinical Oncology Laboratory (OMC), Hospital Arnau de Vilanova, Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO), Valencia, Spain.
Antonio Llombart-CusscacMolecular and Clinical Oncology Laboratory (OMC), Hospital Arnau de Vilanova, Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO), Valencia, Spain.
Gara Verónica Molina-MendozaInstitute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Paterna-Valencia, Spain.
Ana Isabel Aviles-AliaInstitute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain.
Ron GellerInstitute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain.
Laura Mendoza-GarcíaViral immunology laboratory, Biomedicine Department, BICS Unit, Margarita Salas Centre for Biological Research (CIB-CSIC), Madrid, Spain.
María MontoyaViral immunology laboratory, Biomedicine Department, BICS Unit, Margarita Salas Centre for Biological Research (CIB-CSIC), Madrid, Spain.
Eva María Medina-RodríguezInstitute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Paterna-Valencia, Spain.
Yolanda SanzInstitute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Paterna-Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the immediate threat of coronavirus disease 2019 (COVID-19) has diminished, the World Health Organization (WHO) still considers it an important public health concern, as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to circulate at considerable levels. The gut plays an important role in host responses to viral infections, yet its functional role in SARS-CoV-2 infection remains largely unexplored. We conducted a cross-sectional study, including 63 SARS-CoV-2-positive patients and 54 healthy controls, to identify differences in clinically relevant parameters (biochemical and haematological) and in gut microbiota composition, analysed by full-length ribosomal ribonucleic acid (rRNA) operon amplicon sequencing (16S-ITS-23S) on the MinION platform. To evaluate the ability of commensal bacteria inversely associated with COVID-19 to modulate the immune response and intercept SARS-CoV-2's cell entry and infectivity, we performed functional

Indexed as

COVID-19gut microbiotaimmunityinfectionSARS-CoV-2

Identifiers

PMID42827943
PMCPMC13632531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.