Evidence map›Paper›PMID 42827938›Full record

ArticleFrontiers in aging neuroscience2026

Theta-frequency subthalamic nucleus deep brain stimulation selectively improves visual attention in Parkinson's disease.

Yue Lu, Quan Zhang, Hutao Xie, Houyou Fan, Yichen Xu, Guofan Qin, Yutong Zhuang, Jiansong Huang, Anchao Yang, Yin Jiang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yue Lu *Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Quan Zhang *Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hutao XieDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Houyou FanDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yichen XuDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Guofan QinDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yutong ZhuangBeijing Key Laboratory of Neurostimulation, Beijing, China.
Jiansong HuangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Anchao YangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yin JiangBeijing Key Laboratory of Neurostimulation, Beijing, China.
Jianguo ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Visual attention deficits are common but under-recognized in Parkinson's disease (PD), and we investigate whether theta-frequency (5 Hz) STN-DBS differentially modulates visual attention compared with high-frequency (130 Hz) stimulation in PD patients. Methods: Thirty-nine PD patients with bilateral STN-DBS perform an attentional capture task under three stimulation conditions (OFF, low-frequency, high-frequency). Patients are stratified into impaired ( Results: In the impaired group, 5 Hz stimulation significantly improves accuracy in the distractor condition compared with OFF (BF > 1,000), whereas 130 Hz stimulation reduces accuracy (BF = 122.8). This behavioral pattern is paralleled by enhanced P300 amplitude and prolonged latency under 5 Hz stimulation, and suppressed P300 amplitude under 130 Hz stimulation. No significant stimulation effects are observed in the normal group. Conclusion: Theta-frequency STN-DBS selectively improves visual attention in PD with pre-existing attentional deficits, likely by enhancing top-down attentional resource allocation, while high-frequency stimulation impairs performance.

Indexed as

deep brain stimulationParkinson’s diseasesubthalamic nucleustheta-frequencyvisual attention

Identifiers

PMID42827938
PMCPMC13630993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.