ArticleFrontiers in psychology2026
Cognitive appraisal, negative coping, and family resilience among acute leukemia patients and their primary family caregivers: an actor-partner interdependence mediation model of quality of life.
Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study used a dyadic approach to examine the association between cognitive appraisal and quality of life (QoL), and to test whether negative coping and family resilience mediate this association in dyads of acute leukemia (AL) patients and their primary family caregivers. Methods: Three hundred and eight AL patient-caregiver dyads were recruited from five hospitals in China. QoL was measured using the Functional Assessment of Cancer Therapy-Leukemia (FACT-Leu) for patients and the 12-Item Short-Form Health Survey (SF-12) for primary family caregivers. Cognitive appraisal, negative coping, and family resilience were assessed using the Cognitive Appraisal of Health Scale (CAHS), the Trait Coping Style Questionnaire (TCSQ), and the Family Hardiness Index (FHI), respectively. The Actor-Partner Interdependence Mediation Model (APIMeM) was performed in R to examine direct and indirect effects. Results: Patients' QoL was significantly correlated with their own positive coping ( Conclusion: Acute leukemia patients and their primary family caregivers demonstrate divergent stress-coping pathways. For patients, mitigating maladaptive coping such as avoidance and resignation may protect QoL, whereas caregivers may benefit from interventions directly targeting threat perception and emotional burden. Family resilience shows a distinct pattern. It exerts protective effects on patient QoL but not on caregiver QoL, pointing to the need for tailored dyadic psychosocial care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.