ArticleFrontiers in surgery2026
Evaluation of indocyanine green fluorescence guidance in minimally invasive partial nephrectomy stratified by tumor anatomical complexity: a single-center retrospective study.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To evaluate the impact of indocyanine green (ICG) fluorescence guidance on surgical efficiency and renal function during partial nephrectomy (PN), across different tumor anatomical complexities. Methods: We retrospectively reviewed 77 consecutive patients with renal cell carcinoma who underwent minimally invasive PN (MIPN, predominantly robot-assisted, Results: Baseline characteristics were comparable. Overall, operative time was significantly shorter in the ICG group in unadjusted (139.84 vs. 163.57 min; Conclusion: The primary value of ICG fluorescence guidance in MIPN lies in optimizing intraoperative surgical efficiency and shortening operative time; exploratory stratified analyses showed significant operative time reduction with ICG in low-complexity tumors, whereas no significant difference occurred in high-complexity cases. The operative efficiency benefit of ICG in complex cases remains unconfirmed due to limited statistical power. Whether ICG guidance effectively preserves or improves early postoperative renal function remains unknown and requires further investigation.
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