Site-specific N-glycoproteomics reveals alteration of N-glycan structures and heterogeneity to enhance thermally induced gelation characteristics of egg white proteins.

Guang Li, Jiao Wang, Pengyun Gong, Yongguo Jin, Bingkun Zhang, Yuming Guo, Zengpeng Lv

Abstract read

In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guang LiState Key Laboratory of Animal Nutrition and Feeding, China Agricultural University, Beijing 100193, China.

Jiao WangState Key Laboratory of Animal Nutrition and Feeding, China Agricultural University, Beijing 100193, China.

Pengyun GongFetal Cardiopaternal-Maternal Medicine Center, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

Yongguo JinNational Research and Development Center for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, PR China.

Bingkun ZhangState Key Laboratory of Animal Nutrition and Feeding, China Agricultural University, Beijing 100193, China.

Yuming GuoState Key Laboratory of Animal Nutrition and Feeding, China Agricultural University, Beijing 100193, China.

Zengpeng LvState Key Laboratory of Animal Nutrition and Feeding, China Agricultural University, Beijing 100193, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-glycans are complex carbohydrates crucial for the structural integrity and functionality of proteins. Here, we present a high-resolution egg white protein N-glycoproteomic atlas that systematically unveils the microheterogeneity across N-glycosites, glycoproteins, and co-occurring N-glycans. Notably, hawthorn leaf flavonoids (HF) markedly reduced undecorated and high-mannose N-glycans while increasing paucimannose and sialylated-only N-glycans, and these changes strongly correlated with elevated protein stability. Site-specific N-glycan comparative analysis further revealed that HF increased 15 N-glycans at four glycoproteins (such as Hex

Indexed as

Egg white proteinGlycan structureN-glycoproteomicsSite-specific N-glycanThermally induced gel

Identifiers

PMID42827793

DOI10.1016/j.fochx.2026.104473

PMCPMC13631889

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.