Evidence map›Paper›PMID 42827741›Full record

ArticleFrontiers in public health2026

From reference epigenomes to response epigenomes: a public-health case built on the developing brain.

Thomas Hartung

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Thomas HartungCenter for Alternatives to Animal Testing (CAAT), Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.

Funding

GEARs Combining advances in Genomics and Environmental science to accelerate Actionable Research and practice in ASDR01ES034554 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI Christine Ladd-Acosta, HEATHER E VOLK · 2022 to 2026
$9.7M
NEXUS: Network for Exposomics in the U.S.U24ES036819 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Rima Habre, GARY W MILLER · 2024 to 2026
$4.6M
Neurotoxicity due to Environmental complex Metal Mixtures ExposureRF1NS130672 · NINDS · JOHNS HOPKINS UNIVERSITY · PI BISWAL, SHYAM, HARTUNG, THOMAS · 2022 to 2022
$2.4M
NIEHS NIH HHS R01 ES034554NIEHS NIH HHS U24 ES036819NINDS NIH HHS RF1 NS130672
6 · The paper itself

Abstract

Reference epigenome projects, such as the NIH roadmap, ENCODE, and the international human epigenome consortium, have started mapping the baseline regulatory states of human cell types with extraordinary detail. However, these projects were not designed to address the urgent questions posed by exposome science and child-health policy: how these states

Indexed as

BrainEnvironmental ExposureEpigenesis, GeneticEpigenomeEpigenomicsPublic HealthChildHumansdevelopmental neurotoxicityDNA methylationenvironmental healthepigenetic biomarkersexposomegene–environment interactionprecision preventionresponse epigenome

Identifiers

PMID42827741
PMCPMC13630688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.