Evidence map›Paper›PMID 42827720›Full record

ReviewFrontiers in psychology2026

The impact of intergenerational transmission of stigma on the psychological development of minors with HIV-positive parents.

Chenxi Li, Jiali Zhang, Runze Gao, Lin Cai, Tongtong Yang, Ye Wang, Fan Luo

Abstract readReview
In one paragraph

Review in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenxi LiDepartment of Radiology, Chendu Public Health Clinical Medical Center, Chendu, China.
Jiali ZhangDepartment of Psychiatry and Psychology, Beidaihe Rest and Recuperation Center, Qinhuangdao, Hebei, China.
Runze GaoDepartment No.2 of Convalescence, Beidaihe Rest and Recuperation Center, Qinhuangdao, Hebei, China.
Lin CaiDepartment No.2 of Infectious Disease Unit, Chendu Public Health Clinical Medical Center, Chendu, China.
Tongtong YangDepartment No.1 of Infectious Disease Unit Chendu Public Health Clinical Medical Center, Chendu, China.
Ye WangDepartment of Radiology, Chendu Public Health Clinical Medical Center, Chendu, China.
Fan LuoDepartment of Radiology, Chendu Public Health Clinical Medical Center, Chendu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the widespread adoption of antiretroviral therapy, HIV infection has become a chronic, manageable condition, and the population of HIV-positive parents continues to grow. The stigma linked to their condition passes down to their minor children within the family. This harms the children's mental health and makes it harder to prevent and control HIV. This review explores the patterns and mechanisms of intergenerational transmission. It uses stigma theory and ecological systems theory. By examining evidence from around the world and within China, it highlights transmission features and how to adapt interventions specifically for the Chinese context. The results indicate that the stigma experienced by HIV-positive parents exhibits three-dimensional overlap, role specificity, and chronic persistence, with significant population heterogeneity. Intergenerational transmission happens through a four-level chain. It includes family communication and disclosure, parent-child attachment, and family functioning. Next, parental emotions and behaviors come into play. Finally, children's understanding and internalisation of stigma follow. This process shows a dose-response relationship with psychological harm in children. Among existing interventions, family-system-integrated interventions yield the best outcomes, supplemented by individual parental interventions, child protection measures, and social structural interventions; these must be adapted to local cultural and population characteristics. The study shows that we can intervene in the intergenerational passing of disease-related shame. Future research should include longitudinal studies, focus on specific populations, and develop multi-system collaborative intervention models to safeguard the rights of affected children and improve the comprehensive HIV/AIDS prevention and control system.

Indexed as

family systemHIV-positive parentsintergenerational transmissionminor childrenstigma

Identifiers

PMID42827720
PMCPMC13631733

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.