Evidence map›Paper›PMID 42827690›Full record

ArticleMaterials today. Bio2026

An integrated design strategy for structurally stable full-thickness human skin models with regulatory-qualified barrier assessment.

Jihee Won, Young Hoon Son, Hye Joung Kim, Jin-A Kim, Hyocheol Jung, Young Il Park, Seok Chung, Sung-Jin Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jihee WonBiohybrid Systems Group, Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA, 30322, USA.
Young Hoon SonBiohybrid Systems Group, Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA, 30322, USA.
Hye Joung KimSchool of Mechanical Engineering, Korea University, Seoul, Republic of Korea.
Jin-A KimSchool of Mechanical Engineering, Korea University, Seoul, Republic of Korea.
Hyocheol JungDepartment of Specialty Chemicals, Division of Specialty and Bio-Based Chemicals Technology, Korea Research Institute of Chemical Technology, Ulsan, 44412, Republic of Korea.
Young Il ParkDepartment of Specialty Chemicals, Division of Specialty and Bio-Based Chemicals Technology, Korea Research Institute of Chemical Technology, Ulsan, 44412, Republic of Korea.
Seok ChungSchool of Mechanical Engineering, Korea University, Seoul, Republic of Korea.
Sung-Jin ParkBiohybrid Systems Group, Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA, 30322, USA.

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
Reverse Tissue-Manufacturing of the Multicellular Sinoatrial Node OrganoidsR01HL161366 · NHLBI · EMORY UNIVERSITY · PI Sung Jin Park · 2023 to 2026
$2.4M
3D micro-physiological systems for identification of therapeutic myokinesR01AR080169 · NIAMS · EMORY UNIVERSITY · PI Pallavi Bhattaram, Sung Jin Park · 2023 to 2026
$1.9M
NCI NIH HHS P30 CA138292NHLBI NIH HHS R01 HL161366NIAMS NIH HHS R01 AR080169
6 · The paper itself

Abstract

Three-dimensional full-thickness (FT) human skin models provide advantages over reconstructed human epidermis (RhE) by incorporating dermal-epidermal interactions but face persistent challenges with scaffold detachment, contraction, and OECD-compatible barrier validation. In this study, we establish design strategy for

Indexed as

Extracellular matrixFibroblast contractionFull-thickness skin modelHydrogel scaffoldIn vitro skin modelKeratinocyte differentiationpoly(dopamine) coating

Identifiers

PMID42827690
PMCPMC13631632

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.