Evidence map›Paper›PMID 42827663›Full record

ArticleFrontiers in cellular and infection microbiology2026

When metagenomic next-generation sequencing detects

Ping Li, Xiao Yang, Yuxia Chen, Lili Wang, Qiqi Cui, Zhihong Wu, Fenglin Cao

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ping LiDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Xiao YangDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Yuxia ChenJinan AXZE Medical Test Laboratory, Jinan, Shandong, China.
Lili WangDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Qiqi CuiDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Zhihong WuDepartment of Traditional Chinese Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Fenglin CaoSchool of Nursing and Rehabilitation, Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Metagenomic next-generation sequencing (mNGS) increasingly detects Methods: A retrospective analysis from 74 patients at Qilu Hospital of Shandong University from April 2022 to October 2025 was conducted. We assessed mNGS for distinguishing Results: A total of 56 patients with ND and 18 non-ND patients were included. Multivariate logistic regression identified farming exposure, bronchiectasis, and immunocompromised status were significantly associated with ND. An estimated read per million (RPM) thresholds of 56 could distinguish Conclusion: Our study indicated mNGS is a useful tool for distinguishing

Indexed as

High-Throughput Nucleotide SequencingMetagenomicsNocardiaNocardia InfectionsAdultAgedFemaleHumansImmunocompromised HostMaleMiddle AgedRetrospective StudiesRisk Factorsdiagnosisimmune statusmetagenomic next-generation sequencing (mNGS)nocardiosisoptimal threshold value

Identifiers

PMID42827663
PMCPMC13630650

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.