Association of nutritional status assessed by the controlling nutritional status score with clinical outcomes in adults with heart failure with preserved ejection fraction.

Xin Wang, Zhixin Chen, Fen Wen, Chenyu Guo, Fei Jiang, Jianhua Bi, Danni Wang, Shu Jiang

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Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Xin Wang *The Third People's Hospital of Yancheng (The Sixth Affiliated Hospital of Nantong University), Yancheng, China.

Zhixin Chen *Jianhu County Center for Disease Control and Prevention, Yancheng, China.

Fen WenThe Yancheng Clinical College of Xuzhou Medical University and The First people's Hospital of Yancheng, Yancheng, China.

Chenyu Guo *The Yancheng Clinical College of Xuzhou Medical University and The First people's Hospital of Yancheng, Yancheng, China.

Fei JiangDepartment of Epidemiology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, China.

Jianhua BiJiangsu Medical College, Yancheng, China.

Danni WangDepartment of Health Promotion and Behavioral Sciences, School of Public Health, Anhui Medical University, Hefei, China.

Shu JiangThe Yancheng Clinical College of Xuzhou Medical University and The First people's Hospital of Yancheng, Yancheng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the association of the controlling nutritional status (CONUT) score with the 1-year risk of readmission and all-cause mortality in patients with heart failure with preserved ejection fraction (HFpEF) after discharge, and to compare its prognostic performance with the geriatric nutritional risk index (GNRI) and the prognostic nutritional index (PNI). Methods: This multicenter ambispective observational cohort study enrolled adults hospitalized with HFpEF. Patients were stratified according to admission CONUT scores into normal nutrition (0-1 points, Results: A total of 339 patients with HFpEF were analyzed, with a 1-year follow-up completion rate of 96.03%. Higher CONUT risk grades were associated with higher crude rates of 1-year readmission (17.65 to 29.03%, Conclusion: The CONUT score was independently associated with 1-year all-cause mortality in adults with HFpEF and demonstrated significantly better discrimination than GNRI. Its discriminative performance was numerically higher than, but not statistically different from, that of PNI. CONUT may therefore serve as a practical supplementary tool for post-discharge risk stratification, although external validation is required.

Indexed as

controlling nutritional status scoreheart failure with preserved ejection fractionmalnutritionnutritional assessmentprognosis

Identifiers

PMID42827433

DOI10.3389/fnut.2026.1940865

PMCPMC13630525

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